Growth and conidiation of Trichoderma viride are affected by non-steroidal antiinflammatory agents
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu srovnávací studie, časopisecké články
PubMed
8181781
DOI
10.1007/bf02814528
Knihovny.cz E-zdroje
- MeSH
- antiflogistika nesteroidní farmakologie MeSH
- buněčná diferenciace účinky léků MeSH
- druhová specificita MeSH
- mitosporické houby účinky léků fyziologie MeSH
- Saccharomyces cerevisiae účinky léků fyziologie MeSH
- spory hub MeSH
- Trichoderma účinky léků fyziologie MeSH
- Publikační typ
- časopisecké články MeSH
- srovnávací studie MeSH
- Názvy látek
- antiflogistika nesteroidní MeSH
Nonsteroid antiinflammatory agents (NSAIA's) (inhibitors of cyclooxygenase and lipoxygenase) of several structural series inhibited growth of Trichoderma viride. The most potent growth inhibitors were indomethacin and its derivative repanidal which inhibited in the range of 0.1 mmol/L. The weakest inhibitors were acetylsalicylic acid and lysine salicylate which exerted only a weak effect at concentrations above 1 mmol/L. The inhibition of growth was accompanied by a stimulation of conidiation in the dark. A light pulse increased the efficiency of these drugs to stimulate the conidiation. Saccharomyces cerevisiae was as sensitive to NSAIA's as T. viride while Botrytis cinerea was less sensitive. The results indicate that arachidonate metabolism may play a role in the growth of fungi and may participate also in the process of conidiation.
