Relation between resistance to beta-lactam antibiotics and cadmium in salmonellae isolated from pigs
Language English Country United States Media print
Document type Comparative Study, Journal Article
PubMed
8181785
DOI
10.1007/bf02814535
Knihovny.cz E-resources
- MeSH
- Anti-Bacterial Agents pharmacology MeSH
- Drug Resistance, Microbial MeSH
- Bacterial Proteins metabolism MeSH
- beta-Lactamases metabolism MeSH
- beta-Lactams MeSH
- Cadmium pharmacology MeSH
- Swine Diseases microbiology MeSH
- Swine MeSH
- Mercury pharmacology MeSH
- Salmonella drug effects isolation & purification MeSH
- Salmonella Infections, Animal microbiology MeSH
- Silver pharmacology MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- Anti-Bacterial Agents MeSH
- Bacterial Proteins MeSH
- beta-Lactamases MeSH
- beta-Lactams MeSH
- Cadmium MeSH
- Mercury MeSH
- Silver MeSH
Of 50 Salmonella species isolated from pigs, 30 were resistant to cadmium and 18 of these also to azlocillin. The azlocillin-resistant isolates were resistant to cadmium at 80-500 mg/L CdSO4. A broader spectrum of resistance to azlocillin, ampicillin and cephazolin was found in strains resistant to < 200 mg/L CdSO4. Resistance to silver, mercury, chloramphenicol and streptomycin was independent of the resistance to beta-lactam antibiotics and Cd2+. Production and levels of beta-lactamase do not correlate with the spectrum of resistance.
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