Activity of the AIB factor observed in prokaryotic and eukaryotic microorganisms
Language English Country United States Media print
Document type Comparative Study, Journal Article
PubMed
8375780
DOI
10.1007/bf02891697
Knihovny.cz E-resources
- MeSH
- Ascomycota metabolism MeSH
- Basidiomycota metabolism MeSH
- Biological Factors metabolism MeSH
- Butyrates antagonists & inhibitors MeSH
- Species Specificity MeSH
- Hemiterpenes MeSH
- Fungi metabolism MeSH
- Isobutyrates MeSH
- Pentanoic Acids antagonists & inhibitors MeSH
- Streptomyces metabolism MeSH
- Substrate Specificity MeSH
- Publication type
- Journal Article MeSH
- Comparative Study MeSH
- Names of Substances
- 2-methylbutanoic acid MeSH Browser
- Biological Factors MeSH
- Butyrates MeSH
- Hemiterpenes MeSH
- Isobutyrates MeSH
- isobutyric acid MeSH Browser
- isovaleric acid MeSH Browser
- Pentanoic Acids MeSH
- n-pentanoic acid MeSH Browser
Streptomyces cinnamonensis produces a new substance named AIB (for anti-isobutyrate) factor which, on a solid medium, efficiently counteracts toxic concentrations not only of isobutyrate but also of other salts of short-chain monocarboxylic acids. In the present study we demonstrate that the AIB factor activity is widely spread because this effect was positively detected in 25 of 31 randomly chosen microorganisms (streptomycetes, ascomycetes, zygomycetes and basidiomycetes). The AIB factor produced by the tested microorganisms on an agar media allows for germination, growth, and sporulation of the testing Streptomyces coelicolor on an agar medium containing 20 mmol/L acetate, propionate, butyrate, isobutyrate, valerate, isovalerate, and 2-methylbutyrate. The activity of the AIB factor from different sources towards these substances differs.
