Protein profiling of the myocardium exposed to pressure overload from birth
Jazyk angličtina Země Česko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
8789328
Knihovny.cz E-zdroje
- MeSH
- aorta chirurgie MeSH
- kolagen analýza MeSH
- krysa rodu Rattus MeSH
- lehké řetězce myosinu analýza MeSH
- myokard chemie MeSH
- novorozená zvířata MeSH
- potkani Wistar MeSH
- sarkoplazmatické retikulum chemie MeSH
- srdce patofyziologie MeSH
- tlak MeSH
- zvířata MeSH
- Check Tag
- krysa rodu Rattus MeSH
- mužské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- kolagen MeSH
- lehké řetězce myosinu MeSH
Aortic banding induced in 2-day-old (A2) and 6-day-old (A6) male rats increased the left ventricular (LV) weight after 60 days; right ventricular (RV) enlargement occurred in the A2 group only. The concentration of collagenous proteins in the LV was elevated in both experimental groups (more in the A2 rats) at the expenses of sarcoplasmic proteins. Aortic banding also affected the proportion of collagen types (lower collagen I, higher collagen III, V) and myosin light chains (higher LC1/LC2) in the LV. Similar changes of proteins in the RV were less pronounced.
Cardiac phosphocreatine deficiency induced by GPA during postnatal development in rat
