Early ontogeny of immune cells and their functions in the fetal pig
Language English Country Netherlands Media print
Document type Journal Article
PubMed
8988850
DOI
10.1016/s0165-2427(96)05707-8
PII: S0165-2427(96)05707-8
Knihovny.cz E-resources
- MeSH
- Cell Differentiation immunology MeSH
- Embryonic and Fetal Development immunology MeSH
- Granulocytes immunology MeSH
- Immune System cytology immunology MeSH
- Lymphocytes immunology MeSH
- Macrophages immunology MeSH
- Swine MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
The origin of immune cells and their products have been studied in the prenatal period in miniature pigs. Macrophages were first detected on day 25, and myelocytes and lymphoid cells by day 28. Membrane antigens SLA-DR and CD45 were found by day 22, membrane molecules MG-7, 8/1, CD1, CD2 and 74-22 by day 28, Gamma/delta T cells were found initially in extrathymic sites (in the liver). The first gamma/delta T cells were detected as early as 40 days of gestation. The expression of fibronectin, Thy-1 and its message, Ig isotypes and the first induction of IFN alpha were described.
References provided by Crossref.org
The ontogeny of the porcine immune system
Prenatal ontogeny of lymphocyte subpopulations in pigs
