Cellular expression of the cytolytic factor in earthworms Eisenia foetida
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
9541459
DOI
10.1016/s0165-2478(97)00127-2
PII: S0165-2478(97)00127-2
Knihovny.cz E-zdroje
- MeSH
- cytotoxické testy imunologické MeSH
- cytotoxiny biosyntéza MeSH
- lektiny * MeSH
- lipopolysacharidy farmakologie MeSH
- Oligochaeta imunologie MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- coelomic cytolytic factor 1, Eisenia fetida MeSH Prohlížeč
- cytotoxiny MeSH
- lektiny * MeSH
- lipopolysacharidy MeSH
Coelomic fluid of earthworms contains a 42 kDa protein designated CCF-1 (coelomic cytolytic factor 1), which accounts for approximately 40% of cytolytic activity of the entire coelomic fluid. CCF-1 was documented to be present on cells of the mesenchymal lining of the coelomic cavity as well as on free coelomocytes. Both cellular and humoral levels of CCF-1 were significantly increased after parenteral injection of endotoxin. Moreover, CCF-1 seems to be involved in cell mediated cytotoxicity, because cytotoxic activity is blocked in the presence of anti-CCF-1 monoclonal antibody (mAb).
Citace poskytuje Crossref.org
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