Cellular expression of the cytolytic factor in earthworms Eisenia foetida
Language English Country Netherlands Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
9541459
DOI
10.1016/s0165-2478(97)00127-2
PII: S0165-2478(97)00127-2
Knihovny.cz E-resources
- MeSH
- Cytotoxicity Tests, Immunologic MeSH
- Cytotoxins biosynthesis MeSH
- Lectins * MeSH
- Lipopolysaccharides pharmacology MeSH
- Oligochaeta immunology MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- coelomic cytolytic factor 1, Eisenia fetida MeSH Browser
- Cytotoxins MeSH
- Lectins * MeSH
- Lipopolysaccharides MeSH
Coelomic fluid of earthworms contains a 42 kDa protein designated CCF-1 (coelomic cytolytic factor 1), which accounts for approximately 40% of cytolytic activity of the entire coelomic fluid. CCF-1 was documented to be present on cells of the mesenchymal lining of the coelomic cavity as well as on free coelomocytes. Both cellular and humoral levels of CCF-1 were significantly increased after parenteral injection of endotoxin. Moreover, CCF-1 seems to be involved in cell mediated cytotoxicity, because cytotoxic activity is blocked in the presence of anti-CCF-1 monoclonal antibody (mAb).
References provided by Crossref.org
Contribution of Eisenia andrei earthworms in pathogen reduction during vermicomposting
Antimicrobial defense of the earthworm
