NMDA podtyp glutamátového receptoru
[An NMDA glutamate receptor subtype]
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
9601737
- MeSH
- Humans MeSH
- Receptors, N-Methyl-D-Aspartate * drug effects metabolism physiology MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Receptors, N-Methyl-D-Aspartate * MeSH
Glutamate is the main excitatory synaptic transmitter between neurones in the central nervous system. The excitatory effect of glutamate is due to activation of two distinct types of receptor ion channels-AMPA/kainate and NMDA type. This article reviews recent discoveries concerning molecular structure of NMDA receptor channels, its pharmacology and biophysics including excitatory postsynaptic currents mediated by activation of this subtype of glutamate receptor.
