Myoepitheliomas of the skin and soft tissues. Report of 12 cases
Jazyk angličtina Země Německo Médium print
Typ dokumentu kazuistiky, srovnávací studie, časopisecké články
PubMed
10389622
DOI
10.1007/s004280050358
Knihovny.cz E-zdroje
- MeSH
- dospělí MeSH
- imunohistochemie MeSH
- keratiny analýza MeSH
- lidé středního věku MeSH
- lidé MeSH
- myoepiteliální nádor chemie patologie MeSH
- nádory kůže chemie patologie MeSH
- nádory měkkých tkání chemie patologie MeSH
- proteiny S100 analýza MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- senioři nad 80 let MeSH
- senioři MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- srovnávací studie MeSH
- Názvy látek
- keratiny MeSH
- proteiny S100 MeSH
We describe 12 cutaneous and soft tissue myoepitheliomas, most of them in elderly patients. Morphologically the cutaneous and soft tissue myoepitheliomas revealed the same spectrum as their salivary gland counterparts. They were composed of a mixture of spindle, epithelioid and clear myoepithelial cells. Immunohistochemically they were positive to keratins and S-100 protein and reacted inconsistently with antibodies to smooth muscle actin. Morphologically they lacked any folliculo-sebaceous or apocrine differentiation. We believe that they are related to the eccrine type of cutaneous mixed tumours. Most cases had a benign behaviour, but 1 tumour metastasized, and the patient died of the tumour. Myoepitheliomas of soft tissues should be distinguished from other neoplasms with epithelial differentiation and from ossifying fibromyxoid tumour of soft parts, parachordoma and extraskeletal myxoid chondrosarcoma.
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