Visual event-related potentials were simultaneously recorded from different anatomical structures within frontal and temporal lobes in 12 epileptic patients. A simple discrimination task was performed to complement previous studies on the localization of P3 generators in the human brain. The role of multiple cortical structures in the generation of both P3a and P3b components was confirmed. Activities contemporary to a visual P3b were recorded in the hippocampus, amygdala and temporal pole. Anterior cingulate and orbitofrontal cortices-generated activities more closely related in time to the surface P3a. Earlier events related to visual discrimination took place in more lateral sites of the frontal lobe, but their contribution to the scalp P3 remains uncertain. Subsequently, mutual temporal relations among single generators were analyzed. The results suggested a processing-level hierarchy within the neural network for directed attention with a key role played by the dorsolateral prefrontal cortex.

Department of Neurology Masaryk University Saint Annés Hospital Brno Czech Republic

Citace poskytuje Crossref.org

On the time course of synchronization patterns of neuronal discharges in the human brain during cognitive tasks

The posterior medial cortex is involved in visual but not in verbal memory encoding processing: an intracerebral recording study

Directional functional coupling of cerebral rhythms between anterior cingulate and dorsolateral prefrontal areas during rare stimuli: a directed transfer function analysis of human depth EEG signal

Cognitive potentials in the basal ganglia-frontocortical circuits. An intracerebral recording study