Pokroky ve vývoji nových antituberkulotik ze skupin pĕticlenných heterocyklických sloucenin obsahujících jeden druh heteroatomu
[Advances in the development of new antitubercular agents from a group of 5-membered heterocyclic compounds containing one type of heteroatom]
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article, Research Support, Non-U.S. Gov't
PubMed
10566236
- MeSH
- Antitubercular Agents chemical synthesis chemistry MeSH
- Heterocyclic Compounds chemistry MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antitubercular Agents MeSH
- Heterocyclic Compounds MeSH
Tuberculosis and other mycobacterial diseases are considered at present to be one of the prominent problems of health services. Since 1985, and in particular in the 1990s, a search for new structures of antimycobacterial drugs is one of the first and foremost fields of chemotherapeutic research. The present review paper surveys the studies carried out in the field of five-membered heterocyclic compounds containing one species of the heteroatom (furan, thiophene, pyrrol, diazoles, triazoles, tetrazoles, indol, carbazol, and other more complex cyclic compounds of nitrogen and sulfur) since 1984, making use of the journal Chemical Abstracts and original papers.
New antimycobacterial 2,3-dihydro-1-alkylindole-2-thiones
