Enzymatic glycosylation using 6-O-acylated sugar donors and acceptors: beta-N-acetylhexosaminidase-catalysed synthesis of 6-O,N,N'-triacetylchitobiose and 6'-O,N,N'-triacetylchitobiose
Jazyk angličtina Země Nizozemsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
11322728
DOI
10.1016/s0008-6215(01)00027-1
PII: S0008621501000271
Knihovny.cz E-zdroje
- MeSH
- Aspergillus oryzae enzymologie MeSH
- beta-N-acetylhexosaminidasy chemie izolace a purifikace metabolismus MeSH
- disacharidy chemická syntéza chemie MeSH
- glykosylace MeSH
- molekulární struktura MeSH
- Penicillium enzymologie MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- beta-N-acetylhexosaminidasy MeSH
- chitobiose MeSH Prohlížeč
- disacharidy MeSH
p-Nitrophenyl 6-O-acetyl-2-acetamido-2-deoxy-beta-D-glucopyranoside (5a) was used as the glycosyl donor in a beta-N-acetylhexosaminidase-catalysed (from Penicillium brasilianum) glycosylation of GlcNAc yielding 6'-O,N,N'-triacetylchitobiose (6), while 6-O-acetyl-2-acetamido-2-deoxy-beta-D-glucopyranose (3a) served as a selectively protected acceptor in a transglycosylation reaction catalysed by the same enzyme to yield 6-O,N,N'-triacetylchitobiose (4).
Citace poskytuje Crossref.org
Compounds isolated at the Institute of Microbiology in 1989-2001 and future trends
