WD-repeat protein encoding genes among prokaryotes of the Streptomyces genus
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
11347268
DOI
10.1007/bf02817613
Knihovny.cz E-resources
- MeSH
- ATP-Binding Cassette Transporters genetics MeSH
- Bacterial Proteins genetics metabolism MeSH
- DNA Probes MeSH
- Cloning, Molecular MeSH
- Membrane Proteins genetics MeSH
- Molecular Sequence Data MeSH
- GTP-Binding Proteins genetics MeSH
- Repetitive Sequences, Amino Acid genetics physiology MeSH
- Amino Acid Sequence MeSH
- Sequence Analysis, DNA MeSH
- Sequence Alignment MeSH
- Blotting, Southern MeSH
- Streptomyces genetics growth & development MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- ATP-Binding Cassette Transporters MeSH
- Bacterial Proteins MeSH
- DNA Probes MeSH
- Membrane Proteins MeSH
- GTP-Binding Proteins MeSH
- wdlA protein, Streptomyces lincolnensis MeSH Browser
Southern hybridization with probes designed for detection of WD-repeats coding sequences gave positive results in 21 streptomycete strains indicating that WD-repeats encoding genes are massively spread among streptomycetes. One of them, the wdlA gene of Streptomyces lincolnensis, codes for a 971 amino acid protein with seven WD-repeats in its C-terminus, two transmembrane domains and an ATP/GTP binding site upstream of the WD-repeat region.
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