Stúdium lokálnych anestetík CLX. Stanovenie kritickej micelovej koncentrácie (c.m.c.) série piperidinoetylesterov 3-alkoxyfenylkarbámovej kyseliny
[Study of local anesthetics. CLX. Determination of the critical micellar concentration in a series of piperidinoethylesters of 3-alkoxyphenylcarbamic acid]
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article, Research Support, Non-U.S. Gov't
PubMed
12058358
- MeSH
- Anesthetics, Local chemistry MeSH
- Carbamates chemistry MeSH
- Micelles * MeSH
- Spectrophotometry, Ultraviolet MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anesthetics, Local MeSH
- Carbamates MeSH
- Micelles * MeSH
- phenylcarbamic acid MeSH Browser
We have determined the critical micellar concentration (c.m.c) of the derivates type piperidinoethyl esters 3-alkoxy phenylcarbamic in the medium 0.05 mol/l and 0.2/mol/l NaCl for using spectrophotometry methods in the UV region of the spectrum at temperature T = 25 degrees C and pH = 4.5-5.0. We found the parabolic dependence of the -lin(c.m.c.) on the (n) number of the carbon in the alkoxy substituent chain. Further, we have observed the facility formation of the micelle at the solution of 0.2 mol/l than 0.05 mol/l NaCl.
