Ergot alkaloids produced by submerged cultures of Claviceps zizaniae
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
12141870
DOI
10.1021/np010639w
PII: np010639w
Knihovny.cz E-resources
- MeSH
- Claviceps chemistry metabolism MeSH
- Ergolines analysis chemistry isolation & purification MeSH
- Fermentation MeSH
- Mass Spectrometry MeSH
- Molecular Structure MeSH
- Ergot Alkaloids analysis chemistry isolation & purification MeSH
- Nuclear Magnetic Resonance, Biomolecular MeSH
- Spectrophotometry, Ultraviolet MeSH
- Stereoisomerism MeSH
- Chromatography, High Pressure Liquid MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Canada MeSH
- Names of Substances
- ergocryptine MeSH Browser
- Ergolines MeSH
- Ergot Alkaloids MeSH
Two ergopeptine alkaloids, alpha-ergocryptine (1) and its C(8) epimer alpha-ergocryptinine, have been isolated from the mycelium and fermentation broth of submerged cultures of Claviceps zizaniae CCM 8240. The structure of 1 was determined by HPLC/positive ion APCI MS and NMR analysis. Alkaloid concentrations of 10 microg/mL in 14-day-old fermentation broth and 1 mg/g of dry mycelium mass were found. These results are of considerable biotechnological interest since these were the only detectable alkaloids produced. Toxicity of naturally occurring sclerotia of C. zizaniae cannot be excluded.
References provided by Crossref.org
Kinetics of soluble glucan production by Claviceps viridis
