Seronegative Lyme arthritis caused by Borrelia garinii
Jazyk angličtina Země Německo Médium print
Typ dokumentu kazuistiky, časopisecké články
PubMed
12189466
DOI
10.1007/s100670200087
Knihovny.cz E-zdroje
- MeSH
- antigeny bakteriální krev MeSH
- Borrelia burgdorferi komplex genetika imunologie patogenita MeSH
- cefalosporiny terapeutické užití MeSH
- ceftriaxon terapeutické užití MeSH
- DNA bakterií analýza MeSH
- dospělí MeSH
- lidé MeSH
- lymeská nemoc farmakoterapie imunologie patologie MeSH
- sulfasalazin terapeutické užití MeSH
- synoviální tekutina mikrobiologie MeSH
- výsledek terapie MeSH
- Check Tag
- dospělí MeSH
- lidé MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- kazuistiky MeSH
- Názvy látek
- antigeny bakteriální MeSH
- cefalosporiny MeSH
- ceftriaxon MeSH
- DNA bakterií MeSH
- sulfasalazin MeSH
A case of a female patient suffering from Lyme arthritis (LA) without elevated antibody levels to Borrelia burgdorferi sensu lato is reported. Seronegative Lyme arthritis was diagnosed based on the classic clinical manifestations and DNA-detected Borrelia garinii in blood and synovial fluid of the patient, after all other possible causes of the disease had been ruled out. The disease was resistant to the first treatment with antibacterial agents. Six months after the therapy, arthritis still persisted and DNA of Borrelia garinii was repeatedly detected in the synovial fluid and the tissue of the patient. At the same time, antigens or parts of spirochaetes were detected by electron microscopy in the synovial fluid, the tissue and the blood of the patient. The patient was then repeatedly treated by antibiotics and synovectomy has been performed.
Citace poskytuje Crossref.org
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