Ricín--rastlinný toxín s mozným terapeutickým vyuzitím
[Ricin--a plant toxin with potential therapeutic use]
Ceska a Slovenska farmacie.
2004 May ;
53 (3) :
131-4.
Language Slovak Country Czech Republic Media print
Document type English Abstract, Journal Article, Review
Persistent link
https://www.medvik.cz/link/pmid15218734
PubMed
15218734
- MeSH
- Immunotoxins MeSH
- Humans MeSH
- Ricin chemistry pharmacology therapeutic use toxicity MeSH
- Animals MeSH
- Check Tag
- Humans MeSH
- Animals MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Review MeSH
- Names of Substances
- Immunotoxins MeSH
- Ricin MeSH
Ricin is a very toxic RIP II type lectin. As no effective antidote is known, its toxicity could be misused in terrorist actions. The mechanism of the toxic action is currently studied for the preparation of selective immunotoxins, which could be used in the therapy of various cancer diseases or HIV infection. There are promising in vitro results, but some adverse in vivo effects limit the use of these preparations in real therapy.
