Cytogenetic mapping of immunity-related genes in the domestic horse
Jazyk angličtina Země Anglie, Velká Británie Médium print
Typ dokumentu srovnávací studie, časopisecké články, práce podpořená grantem
PubMed
16293125
DOI
10.1111/j.1365-2052.2005.01348.x
PII: AGE1348
Knihovny.cz E-zdroje
- MeSH
- DNA primery MeSH
- druhová specificita MeSH
- geny genetika imunologie MeSH
- hybridizace in situ fluorescenční MeSH
- koně genetika imunologie MeSH
- lidé MeSH
- mapování chromozomů * MeSH
- mikrosatelitní repetice genetika MeSH
- syntenie genetika MeSH
- zvířata MeSH
- Check Tag
- lidé MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- srovnávací studie MeSH
- Názvy látek
- DNA primery MeSH
Chromosomal locations of 19 horse immunity-related loci (CASP1, CD14, EIF5A, FCER1A, IFNG, IL12A, IL12B, IL12RB2, IL1A, IL23A, IL4, IL6, MMP7, MS4A2, MYD88, NOS2A, PTGS2, TFRC and TLR2) were determined by fluorescence in situ hybridization. For IFNG and PTGS2, this study is a confirmation of their previously reported position. In addition, microsatellite (HMBr1) was localized in the same region as IFNG. All genes were assigned to regions of conserved synteny and the data obtained in this study enhance the comparative human-horse map. Cytogenetic localization of IL6 to ECA4q14-q21.1 suggested a new breakage point that changes the order of loci compared with HSA7. The map assignments of these loci serve as anchors for other loci and will aid in the search for candidate genes associated with traits in the horse.
Citace poskytuje Crossref.org
Subchromosomal karyotype evolution in Equidae
