Yersinia Yop-specific IgA antibodies in Hungarian blood donors
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
16295667
DOI
10.1007/bf02931576
Knihovny.cz E-zdroje
- MeSH
- aglutinační testy MeSH
- dárci krve * MeSH
- dospělí MeSH
- ELISA MeSH
- imunoblotting MeSH
- imunoglobulin A krev MeSH
- infekce yersiniemi epidemiologie imunologie MeSH
- lidé středního věku MeSH
- lidé MeSH
- proteiny vnější bakteriální membrány imunologie MeSH
- protilátky bakteriální krev MeSH
- specificita protilátek MeSH
- Yersinia enterocolitica imunologie MeSH
- Yersinia pseudotuberculosis imunologie MeSH
- Check Tag
- dospělí MeSH
- lidé středního věku MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Geografické názvy
- Maďarsko epidemiologie MeSH
- Názvy látek
- imunoglobulin A MeSH
- proteiny vnější bakteriální membrány MeSH
- protilátky bakteriální MeSH
Sera of 112 healthy Hungarian blood donors were tested for the presence of Yersinia enterocolitica and Y. pseudotuberculosis-specific agglutinins by tube agglutination, and for that of yersinia outer membrane protein (Yop)-specific IgA antibodies by ELISA. The positive results of this latter assay were confirmed by immunoblot. Only one sample gave a positive agglutination reaction with Y. enterocolitica antigen (group 03) and four exhibited an equivocal reaction with Y. pseudotuberculosis antigens (groups II and IV). Contrary to the low incidence of agglutinins, 15.1% of the samples showed a positive Yop-specific IgA reaction, while further 5.3% samples fell into the equivocal range by ELISA (17 and 6 specimens, respectively). Eleven of these samples (9.8% of all specimens tested) were also positive by immunoblot for the presence of Yop-specific IgA antibodies. These data suggest a higher incidence of yersinia infections than the 1.0-1.4 per 10(5) population predicted on the basis of stool culture results.
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