Role of Yersinia pseudotuberculosis outer proteins (Yops) in murine humoral immune response
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- autoprotilátky krev imunologie MeSH
- bakteriální proteiny imunologie MeSH
- fosforylcholin imunologie MeSH
- imunoglobulin G krev imunologie MeSH
- imunoglobulin M krev imunologie MeSH
- infekce vyvolané Yersinia pseudotuberculosis krev imunologie MeSH
- kardiolipiny imunologie MeSH
- myelinová pochva imunologie MeSH
- myši MeSH
- protein-serin-threoninkinasy imunologie MeSH
- proteiny vnější bakteriální membrány imunologie MeSH
- protilátky bakteriální krev imunologie MeSH
- specificita protilátek MeSH
- thyreoglobulin imunologie MeSH
- tyrosinfosfatasy imunologie MeSH
- Yersinia pseudotuberculosis imunologie MeSH
- zvířata MeSH
- Check Tag
- myši MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- autoprotilátky MeSH
- bakteriální proteiny MeSH
- fosforylcholin MeSH
- imunoglobulin G MeSH
- imunoglobulin M MeSH
- kardiolipiny MeSH
- protein-serin-threoninkinasy MeSH
- proteiny vnější bakteriální membrány MeSH
- protilátky bakteriální MeSH
- thyreoglobulin MeSH
- tyrosinfosfatasy MeSH
- yopH protein, Yersinia MeSH Prohlížeč
- YopP protein, Yersinia MeSH Prohlížeč
- ypkA protein, Yersinia MeSH Prohlížeč
The infection of mice with the wild-type (WT) strain of Y. pseudotuberculosis did not induce polyclonal activation of B lymphocytes. Suppression in the production of certain isotypes of Ig was observed, provoked mainly by YopH, YopJ and YpkA. The WT strain induced a progressive increase in the serum-specific IgG, which peaked after 4 weeks after infection, IgM being produced only after 1 week. Autoantibodies against phosphorylcholine, myelin, thyroglobulin and cardiolipin could be detected in the serum of mice infected with the WT strain. The infection of mice provoked suppression in the production of immunoglobulins by splenic B cells and that YopH, YopJ and YpkA must be involved here.
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Infect Immun. 1986 Feb;51(2):445-54 PubMed
J Med Microbiol. 1996 Apr;44(4):285-94 PubMed
Infect Immun. 1986 Nov;54(2):561-7 PubMed
Autoimmunity. 2003 Aug;36(5):261-8 PubMed
Folia Microbiol (Praha). 2005;50(3):269-72 PubMed
J Immunol. 1997 Aug 15;159(4):1853-9 PubMed
Cell. 2006 Sep 8;126(5):869-80 PubMed
Mol Microbiol. 2000 May;36(3):737-48 PubMed
Infect Immun. 1996 Mar;64(3):829-35 PubMed
FEBS Lett. 2006 Jan 9;580(1):179-83 PubMed
Arch Immunol Ther Exp (Warsz). 2002;50(2):131-7 PubMed
Mol Microbiol. 1998 Mar;27(5):953-65 PubMed
Mol Microbiol. 1998 Jun;28(6):1067-79 PubMed
J Biol Chem. 2004 Jun 11;279(24):25134-42 PubMed
Contrib Microbiol Immunol. 1991;12:117-22 PubMed
Arthritis Rheum. 1978 Nov-Dec;21(8):904-8 PubMed
Infect Immun. 1990 Oct;58(10):3262-71 PubMed
Infect Immun. 2004 Aug;72(8):4589-602 PubMed
Curr Opin Microbiol. 2006 Feb;9(1):55-61 PubMed
Infect Immun. 1991 Dec;59(12):4562-9 PubMed
J Exp Med. 2005 Feb 7;201(3):361-71 PubMed
Immunobiology. 1993 Jan;187(1-2):1-16 PubMed
Immunol Rev. 1985 Aug;86:47-70 PubMed
Ann Rheum Dis. 1994 Aug;53(8):535-9 PubMed
Infect Immun. 2004 Sep;72(9):5227-34 PubMed
Infect Immun. 2003 Aug;71(8):4595-607 PubMed
Microbiol Immunol. 2002;46(2):95-100 PubMed
Proc Natl Acad Sci U S A. 2000 Aug 15;97(17):9431-6 PubMed
Microbiol Mol Biol Rev. 1998 Dec;62(4):1315-52 PubMed
Infect Immun. 1989 Aug;57(8):2534-41 PubMed
J Biol Chem. 2004 Feb 6;279(6):4922-8 PubMed
J Immunol Methods. 1992 Aug 10;152(2):227-36 PubMed
Infect Immun. 1988 Aug;56(8):2139-43 PubMed
J Immunol Methods. 1983 Dec 16;65(1-2):109-21 PubMed
J Exp Med. 1999 Nov 1;190(9):1343-50 PubMed
EMBO J. 2001 Oct 1;20(19):5373-82 PubMed
Nature. 1993 Feb 25;361(6414):730-2 PubMed
Int J Med Microbiol. 2008 Jan;298(1-2):59-67 PubMed
