Genotypic characterisation of vancomycin-resistant Enterococcus faecium isolates from haemato-oncological patients at Olomouc University Hospital, Czech Republic
Jazyk angličtina Země Velká Británie, Anglie Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
16524412
DOI
10.1111/j.1469-0691.2006.01365.x
PII: S1198-743X(14)61603-7
Knihovny.cz E-zdroje
- MeSH
- Enterococcus faecalis klasifikace izolace a purifikace MeSH
- Enterococcus faecium klasifikace genetika izolace a purifikace MeSH
- genotyp MeSH
- grampozitivní bakteriální infekce mikrobiologie MeSH
- hematologické nádory MeSH
- infekce spojené se zdravotní péčí mikrobiologie MeSH
- lidé MeSH
- nádory MeSH
- onkologická péče - zařízení * MeSH
- polymorfismus délky restrikčních fragmentů MeSH
- rezistence na vankomycin genetika MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
This study describes the first molecular characterisation of clinical isolates of vancomycin-resistant enterococci (VRE) in the Czech Republic. Of 2647 patient isolates of Enterococcus spp. from 1997-2002, 121 (4.6%) were identified as VRE. The most common isolates were VanA+ Enterococcus faecium (78%) and VanB+ Enterococcus faecalis (10%). In addition, five VanA+ E. faecium isolates were obtained from environmental and staff sampling. Macrorestriction analysis of SmaI restriction fragment length polymorphism was performed for 54 VanA+ E. faecium clinical isolates and the five VanA+ E. faecium environmental isolates. Thirty-two unique restriction endonuclease patterns were identified, including two predominant clonal types represented by five or more isolates. Two environmental VanA+ E. faecium isolates were closely related to two patient isolates, which had an identical SmaI macrorestriction pattern. The results indicated potential survival of strains in the hospital environment and possible subsequent transmission to hospitalised patients.
Citace poskytuje Crossref.org
Analysis of Vancomycin-Resistant Enterococci in Hemato-Oncological Patients