Production of Yarrowia lipolytica Nha2 Na+/H+ antiporter improves the salt tolerance of Saccharomyces cerevisiae
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18450222
DOI
10.1007/bf02932189
Knihovny.cz E-resources
- MeSH
- Antifungal Agents pharmacology MeSH
- Gene Expression MeSH
- Fungal Proteins genetics metabolism MeSH
- Cloning, Molecular MeSH
- Sodium-Hydrogen Exchangers genetics metabolism MeSH
- Recombinant Proteins genetics metabolism MeSH
- Saccharomyces cerevisiae drug effects genetics growth & development metabolism MeSH
- Salts pharmacology MeSH
- Yarrowia enzymology genetics MeSH
- Zygosaccharomyces enzymology genetics MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antifungal Agents MeSH
- Fungal Proteins MeSH
- Sodium-Hydrogen Exchangers MeSH
- Recombinant Proteins MeSH
- Salts MeSH
Yarrowia lipolytica plasma-membrane Na+/H+ antiporter, encoded by the YlNHA2 gene, is a very efficient exporter of surplus sodium from the cytosol. Its heterologous expression in Saccharomyces cerevisiae wild-type laboratory strains increased their sodium tolerance more efficiently than the expression of ZrSod2-22 antiporter from the osmotolerant yeast Zygosaccharomvces rouxii.
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