Three-dimensional arrangement of the capillary bed and its relationship to microrheology in the terminal villi of normal term placenta
Language English Country Netherlands Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18768220
DOI
10.1016/j.placenta.2008.07.004
PII: S0143-4004(08)00209-9
Knihovny.cz E-resources
- MeSH
- Chorionic Villi blood supply MeSH
- Capillaries anatomy & histology MeSH
- Microscopy, Confocal MeSH
- Humans MeSH
- Microcirculation physiology MeSH
- Placenta blood supply MeSH
- Rheology MeSH
- Pregnancy MeSH
- Check Tag
- Humans MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
Spatial arrangement of the capillary bed, manifestations of its growth and symmetry of capillary branching were studied in peripheral villi of normal human placenta at term using confocal microscopy and image analysis. Unlike the model that has been accepted so far, it was shown that the arrangement of the capillary bed in terminal villi varied from simple, U-like loops to a richly branched network. Three different categories of terminal villi (TV) were recognised: Signs of capillary elongation and sprouting were observed in the villous capillary bed. Based on the assessment of the mean cross-sectional areas of capillaries constituting simple, Y-like capillary bifurcation in terminal villi, the capillary branching was found to be asymmetric. Therefore, we conclude that the conditions for the "plasma skimming" effect are met in human placenta.
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