Drugs during lactation accenting boron exposure
Language English Country Sweden Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
18987605
PII: NEL290508A36
Knihovny.cz E-resources
- MeSH
- Anti-Infective Agents, Local adverse effects metabolism MeSH
- Anticonvulsants adverse effects pharmacokinetics MeSH
- Biological Availability MeSH
- Adult MeSH
- Epilepsy complications MeSH
- Drug Information Services statistics & numerical data MeSH
- Breast Feeding adverse effects MeSH
- Boric Acids adverse effects metabolism MeSH
- Pharmaceutical Preparations metabolism MeSH
- Humans MeSH
- Milk, Human chemistry MeSH
- Drug-Related Side Effects and Adverse Reactions * MeSH
- Infant, Newborn MeSH
- Half-Life MeSH
- Pregnancy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Anti-Infective Agents, Local MeSH
- Anticonvulsants MeSH
- boric acid MeSH Browser
- Boric Acids MeSH
- Pharmaceutical Preparations MeSH
OBJECTIVES: The benefits of breastfeeding are generally accepted. Risk of drug usage for baby due to lactation is well assessed minimally in certain cases. However, information given about drugs are often insufficient, frustrating, and not recommending lactation. In Czech Teratology Information Service (CZTIS) counselling we use these information. RESULTS: We have given advice in 58 cases inquiring the CZTIS about the risk of drug exposure during lactation. The most frequent queries were on chronic disease treatment following the drug exposure during pregnancy. Remaining cases were associated with acute infections. Mothers suffered from idiopathic bowel disease and psychiatric patients want to be informed before delivery about possibility to breastfeed their babies. Treatment of epilepsy, another frequent disease, is associated with better level of knowledge of both, neurologists and patients. Breastfeeding is recommended according to management in care of epileptic women. CONCLUSION: In our counselling we consider the factors which are involved in drug transfer in the milk and mechanisms and steps of transfer as well. We follow the classification of drugs during lactation by their effect on infants: absolutely contraindicated, temporary cessation of breastfeeding, drugs of special concern and drugs compatible with breastfeeding.