- MeSH
- Drug Information Services * statistics & numerical data MeSH
- Humans MeSH
- Check Tag
- Humans MeSH
- Publication type
- Tables MeSH
- Geographicals
- Czech Republic MeSH
- MeSH
- Information Seeking Behavior * MeSH
- Pharmacists MeSH
- Consumer Health Information MeSH
- Drug Information Services * statistics & numerical data utilization MeSH
- Internet MeSH
- Pharmaceutical Preparations * MeSH
- Physicians MeSH
- Humans MeSH
- Drug-Related Side Effects and Adverse Reactions MeSH
- Mandatory Reporting MeSH
- Patients MeSH
- Surveys and Questionnaires MeSH
- Information Dissemination MeSH
- Information Storage and Retrieval methods statistics & numerical data MeSH
- Check Tag
- Humans MeSH
Current practice guidelines recommend the routine use of several effective cardiac medications in hospital survivors of acute myocardial infarction (AMI). METHODS: We explored a recent 5-year (2000-2005) trend in hospital use of aspirin, beta-blockers, angiotensin-converting enzyme (ACE) inhibitors, lipid-lowering agents, and combinations thereof, in 26 413 adult men and women without contraindications to any of these therapies discharged after AMI from hospitals located in 14 countries that were included in the Global Registry of Acute Coronary Events. RESULTS: Relatively steady increases in the use of ACE inhibitors, beta-blockers, and statin therapy were observed over time, with particularly marked increases in the use of lipid-lowering therapy (from 45% in 2000 to 85% in 2005). Aspirin use remained high (by approximately 95% of patients after AMI) during all periods examined. The percentage of hospital survivors treated with all 4 cardiac medications increased from 23% in 2000 to 58% during 2005. Advancing age (>/= 65 years), female sex, medical history of heart failure or stroke, and development of atrial fibrillation during hospitalization were associated with underuse of combination medical therapy. Relatively similar factors were associated with the underuse of combination medical therapy in patients with ST-segment elevation AMI and non-ST-segment elevation AMI. CONCLUSIONS: Our results suggest encouraging increases over time in the use of combination medical therapy in patients hospitalized with AMI without contraindications to these medications. Educational efforts designed to increase the use of these therapies, as well as efforts to simplify medication regimens and enhance rates of adherence, remain warranted.
- MeSH
- Fibrinolytic Agents therapeutic use MeSH
- Drug Utilization Review trends MeSH
- Inpatients MeSH
- Hypolipidemic Agents therapeutic use MeSH
- Myocardial Infarction drug therapy MeSH
- Drug Information Services statistics & numerical data MeSH
- Angiotensin-Converting Enzyme Inhibitors therapeutic use MeSH
- Drug Prescriptions statistics & numerical data MeSH
- Middle Aged MeSH
- Humans MeSH
- Retrospective Studies MeSH
- Aged MeSH
- World Health Organization MeSH
- Check Tag
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Abstracts MeSH
OBJECTIVES: The benefits of breastfeeding are generally accepted. Risk of drug usage for baby due to lactation is well assessed minimally in certain cases. However, information given about drugs are often insufficient, frustrating, and not recommending lactation. In Czech Teratology Information Service (CZTIS) counselling we use these information. RESULTS: We have given advice in 58 cases inquiring the CZTIS about the risk of drug exposure during lactation. The most frequent queries were on chronic disease treatment following the drug exposure during pregnancy. Remaining cases were associated with acute infections. Mothers suffered from idiopathic bowel disease and psychiatric patients want to be informed before delivery about possibility to breastfeed their babies. Treatment of epilepsy, another frequent disease, is associated with better level of knowledge of both, neurologists and patients. Breastfeeding is recommended according to management in care of epileptic women. CONCLUSION: In our counselling we consider the factors which are involved in drug transfer in the milk and mechanisms and steps of transfer as well. We follow the classification of drugs during lactation by their effect on infants: absolutely contraindicated, temporary cessation of breastfeeding, drugs of special concern and drugs compatible with breastfeeding.
- MeSH
- Anti-Infective Agents, Local metabolism adverse effects MeSH
- Anticonvulsants pharmacokinetics adverse effects MeSH
- Biological Availability MeSH
- Adult MeSH
- Epilepsy complications MeSH
- Drug Information Services statistics & numerical data MeSH
- Breast Feeding adverse effects MeSH
- Boric Acids metabolism adverse effects MeSH
- Pharmaceutical Preparations metabolism MeSH
- Humans MeSH
- Milk, Human chemistry MeSH
- Drug-Related Side Effects and Adverse Reactions MeSH
- Infant, Newborn MeSH
- Half-Life MeSH
- Pregnancy MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Infant, Newborn MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- MeSH
- Drug Therapy MeSH
- Drug Information Services organization & administration statistics & numerical data utilization MeSH
- Internet MeSH
- Counseling MeSH
- Risk MeSH
- Pregnancy MeSH
- Check Tag
- Pregnancy MeSH
- Publication type
- Review MeSH
Znalost pacientů o perorálních monokomponentních OTC přípravcích s obsahem ibuprofenu, kterési kupují pro sebe, byla hodnocena ve vztahu k tomu, jakým způsobem probíhala komunikacefarmaceut (farm. laborant) – pacient při výdeji v lékárně. Odpovědi respondentů byly zpracoványzvlášť pro skupinu těch, kteří si kupují přípravek poprvé, a těch, kteří ho již dříve pro samoléčenípoužívali. Znalost kontraindikací a nežádoucích účinků (posuzováno odděleně) byla zjištěna v obouskupinách respondentů vyšší než 50 %. Pacienti, kteří užívají přípravek opakovaně, však udávajísoučasnou neznalost nežádoucích účinků a kontraindikací jen 32,2 %, oproti novým uživatelům(60,0 %). Pacienti, kteří neznají ani kontraindikace ani nežádoucí účinky kupovaného přípravku, sipřesto myslí, že mají dostatek informací k tomu, aby jejich samoléčení bylo bezpečné (88,9 %opakovaných a 80,0 % nových uživatelů). Přibližně čtvrtina respondentů v obou hodnocených skupináchuvádí, že při výdeji nedostali v lékárně žádnou informaci. Pacienti přistupují k nákupu OTCpřípravku pasivně a téměř ve 40 % nevyužívají možnosti sami se na potřebné informace zeptat.Informace získané v lékárně považuje téměř 85 % respondentů z obou skupin za dostatečné. Farmaceuti(farm. laboranti) při výdeji OTC přípravku ve 45 % případů nezjišťují, zda pacient jižpřípravek užíval a zda o něm má nějaké znalosti. Úroveň poradenství při samoléčení by se v ČRměla zefektivnit.
Knowledge of patients about oral single-component OTC preparations containing ibuprofen, boughtfor their own use,was evaluated in relation to the manner of the process of communication betweenthe pharmacist (laboratory assistant) – patient during the supply at the pharmacy. The answers ofrespondents were processed separately for the group of those who bought the preparation for thefirst time and those who had already used it for self-medication. The knowledge of contraindicationsand undesirable effects (judged separately) was found to be higher than 50 % in both groups ofrespondents. Nevertheless, the patients who use the preparation repeatedly state simultaneousignorance of undesirable effects and contraindications only in 32.2 %, in contrast to the new users(60.0 %). The patients who know neither contraindications nor undesirable effects of the preparationwhich they buy nevertheless think that they have enough information so that their self-medicationcan be safe (88.9 % of patients using the preparation repeatedly and 80.0 % of new users).Approximately a quarter of respondents in both groups under evaluation state that during thesupply in the pharmacy they were not given any piece of information. Patients are passive whenbuying an OTC preparation and nearly 40 % of them do not use the opportunity to ask for pertinentinformation themselves. Nearly 85 % of respondents from both groups consider information gainedfrom the pharmacy to be sufficient. When supplying an OTC preparation, in 45 % of casespharmacists (laboratory assistants) do not inquire whether the patient have already used thepreparation, or whether he or she knows anything about it. The standard of counselling onself-medication in the Czech Republic should thus become more effective.
- Keywords
- APO-IBUPROFEN, BRUFEN, NUROFEN,
- MeSH
- Ibuprofen therapeutic use MeSH
- Drug Information Services statistics & numerical data trends MeSH
- Pharmaceutical Preparations standards MeSH
- Humans MeSH
- Drug-Related Side Effects and Adverse Reactions MeSH
- Counseling statistics & numerical data trends MeSH
- Self Medication adverse effects statistics & numerical data MeSH
- Check Tag
- Humans MeSH
- Publication type
- Comparative Study MeSH
