The aim of the study was to evaluate acute toxic effects of the preparation Sencor 70 WG (metribuzin 70% W/V) on hematological, biochemical indices and histology of the common carp (Cyprinus carpio L.). In carp exposed for 96 h to Sencor 70 WG in the concentration of 250.2 mg/L, showed significantly lower (p<0.01) values of plasma total proteins, albumins, total globulins, triacylglycerols, lactate dehydrogenase, lactate, inorganic phosphate, hematocrit, hemoglobin concentration, mean erythrocyte volume, the leucocrite value, lymphocyte, and significantly higher (p<0.01) values of glucose, ammonia, calcium, monocytes, neutrophile granulocytes, developmental forms myeloid sequence and basophiles compared to the control group. Histopathological examination revealed hyaline degeneration of the epithelial cells of renal tubules of the caudal kidney. This alteration of kidney resulted in hypoproteinemia, followed by generation of transudate in body cavity.

Research Institute of Fish Culture and Hydrobiology Vodnany University of South Bohemia Ceske Budejovice Zatisi 728 2 389 25 Vodnany Czech Republic

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