Norsesquiterpene hydrocarbon, chemical composition and antimicrobial activity of Rhaponticum carthamoides root essential oil
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
19195668
DOI
10.1016/j.phytochem.2008.12.018
PII: S0031-9422(08)00608-0
Knihovny.cz E-resources
- MeSH
- Anti-Infective Agents chemistry isolation & purification pharmacology MeSH
- Bacteria drug effects MeSH
- Chromatography, Gas MeSH
- Plant Roots chemistry MeSH
- Yeasts drug effects MeSH
- Leuzea chemistry MeSH
- Magnetic Resonance Spectroscopy MeSH
- Microbial Sensitivity Tests MeSH
- Molecular Structure MeSH
- Oils, Volatile chemistry isolation & purification pharmacology MeSH
- Plant Oils chemistry isolation & purification pharmacology MeSH
- Gas Chromatography-Mass Spectrometry MeSH
- Spectroscopy, Fourier Transform Infrared MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Anti-Infective Agents MeSH
- Oils, Volatile MeSH
- Plant Oils MeSH
A detailed analysis of Rhaponticum carthamoides (Willd.) Iljin root essential oil was carried out by GC, GC-MS and GC-FTIR techniques. In total, 30 components were identified, accounting for 98.0% of total volatiles. A norsesquiterpene 13-norcypera-1(5),11(12)-diene (22.6%), followed by aplotaxene (21.2%) and cyperene (17.9%), were isolated and their structures confirmed by 1D and 2D-NMR spectra (COSY, ROESY, HSQC, HMBC and INADEQUATE). Selinene type sesquiterpenes and aliphatic hydrocarbons were among minor constituents of the essential oil. The oil exhibited antimicrobial activity against 5 of 9 strains of bacteria and yeast, when tested using broth micro-dilution method. Minimum inhibitory concentrations ranged between 32 and 256 microg/ml.
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