Nucleolar transplantation in oocytes and zygotes: challenges for further research
Jazyk angličtina Země Velká Británie, Anglie Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
19819895
DOI
10.1093/molehr/gap088
PII: gap088
Knihovny.cz E-zdroje
- MeSH
- asistovaná reprodukce MeSH
- buněčné jadérko transplantace MeSH
- embryo savčí cytologie MeSH
- lidé MeSH
- oocyty cytologie MeSH
- zvířata MeSH
- zygota cytologie MeSH
- Check Tag
- lidé MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
In germinal vesicles of immature mammalian oocytes, including humans, as well as in pronuclei in 1-cell stage embryos, prominent nuclear organelles, nucleoli, can be easily detected even under a relatively low magnification. In humans, it has been clearly documented that their number, position and distribution in pronuclei can be used as an indicator of embryonic developmental potential. In the light of some recent experiments showing the feasibility of nucleolar manipulation we discuss here if these new approaches can be used to rescue those embryos with abnormal pronuclear nucleolar patterns.
Citace poskytuje Crossref.org
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