History of incidence of autoimmune and oncological diseases in identical female twins
Language English Country Denmark Media print-electronic
Document type Case Reports, Journal Article
PubMed
19821804
DOI
10.1111/j.1600-0897.2009.00753.x
PII: AJI753
Knihovny.cz E-resources
- MeSH
- Adult MeSH
- Twins, Monozygotic * MeSH
- Fatal Outcome MeSH
- Humans MeSH
- Uterine Cervical Neoplasms complications diagnosis pathology physiopathology MeSH
- Vaginal Neoplasms complications diagnosis pathology physiopathology MeSH
- Diseases in Twins * MeSH
- Precancerous Conditions complications diagnosis pathology physiopathology MeSH
- Retrospective Studies MeSH
- Sjogren's Syndrome complications diagnosis pathology physiopathology MeSH
- Carcinoma, Squamous Cell complications diagnosis pathology physiopathology MeSH
- Lupus Erythematosus, Systemic complications diagnosis pathology physiopathology MeSH
- Pregnancy MeSH
- Delivery, Obstetric MeSH
- Check Tag
- Adult MeSH
- Humans MeSH
- Pregnancy MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Case Reports MeSH
PROBLEM: The aim of study was to investigate identical female twins born in 1977 suffered from autoimmune diseases (twin A - Sjogren's syndrome, and twin B - systemic lupus erythematosus). METHOD OF STUDY: It was refer retrospective analysis of both sisters suffered beside autoimmune alterations (Sjogren's syndrome and systemic lupus erythematosus) also from gynecological diseases (twin A - praecancerosis of cervix uteri, twin B - carcinoma vaginae). RESULTS: Relationships between disease activities and severities in the female twins were similar and the treatments were directed according to clinical symptoms and laboratory results. Dramatic change, unfortunately, occurred with twin B. The reason may be the association between SLE activity (lupus nephritis), hematological complication (leukopenia) and oncological vaginal recidivation. CONCLUSION: Association between autoimmune disease and gynecological cancer (or praecancerosis) is major risk than without immunology deviation. Twin A is periodically gynecologically observed.
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