Adipokinetic hormone (Pyrap-AKH) enhances the effect of a pyrethroid insecticide against the firebug Pyrrhocoris apterus
Language English Country Great Britain, England Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
20013955
DOI
10.1002/ps.1894
Knihovny.cz E-resources
- MeSH
- Central Nervous System drug effects metabolism MeSH
- Stress, Physiological drug effects MeSH
- Hemolymph metabolism MeSH
- Heteroptera * drug effects metabolism physiology MeSH
- Insect Hormones blood metabolism pharmacology MeSH
- Insecticides * administration & dosage MeSH
- Pyrrolidonecarboxylic Acid analogs & derivatives blood metabolism pharmacology MeSH
- Oligopeptides blood metabolism pharmacology MeSH
- Carbon Dioxide metabolism MeSH
- Permethrin * administration & dosage MeSH
- Pesticide Synergists blood metabolism pharmacology MeSH
- Animals MeSH
- Check Tag
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- adipokinetic hormone MeSH Browser
- Insect Hormones MeSH
- Insecticides * MeSH
- Pyrrolidonecarboxylic Acid MeSH
- Oligopeptides MeSH
- Carbon Dioxide MeSH
- Permethrin * MeSH
- Pesticide Synergists MeSH
BACKGROUND: Adipokinetic hormones (AKHs) are insect neuropetides controlling stress situations including those elicited by insecticide treatment. The effect of Pyrap-AKH on the mortality of the firebug Pyrrhocoris apterus (L.) treated with the insecticide permethrin (Ambush 25 EC) was studied. RESULTS: Coinjection of 50 ng permethrin with 80 pmol Pyrap-AKH induced a significant 2.3-fold increase in bug mortality compared with the insecticide alone. The results were confirmed by topical coapplication of both agents (400 ng and 80 pmol respectively). Injections of 50 and 100 ng permethrin elicited a significant increase in the AKH level in CNS and the haemolymph. The results indicate an involvement of AKH in stress response to permethrin. The enhanced effect of insecticide by AKH treatments probably results from the stimulatory role in bug metabolism: carbon dioxide production was increased 3.5- and 2.5-fold respectively 1 and 3 h after permethrin treatment, and 4.3- and 3.4-fold after the permethrin plus AKH cotreatment, compared with the control. CONCLUSION: The elevation of metabolism could intensify the permethrin action by its faster penetration into tissues and by stimulation of biochemically active cells, and could be a reason for enhanced action of permethrin after its cotreatment with Pyrap-AKH.
Institute of Entomology Biology Centre Academy of Sciences CZ 370 05 Ceské Budejovice Czech Republic
References provided by Crossref.org
Insect Body Defence Reactions against Bee Venom: Do Adipokinetic Hormones Play a Role?
Hormonal Regulation of Response to Oxidative Stress in Insects-An Update
