The effects of thiamine inhibition on ruminal fermentation: a preliminary study
Language English Country United States Media print-electronic
Document type Journal Article
- MeSH
- Rumen metabolism microbiology MeSH
- Fermentation MeSH
- Methane antagonists & inhibitors MeSH
- Cattle MeSH
- Thiamine antagonists & inhibitors MeSH
- Animals MeSH
- Check Tag
- Cattle MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Names of Substances
- Methane MeSH
- Thiamine MeSH
Inhibition of methanogenesis in ruminal cultures was attempted by hindering thiamine availability through its degradation by 'polyphenols' and competition for active sites on enzymes and transporters using thiamine structural analogs. Effects on fermentation were small and not consistently reversed by adding thiamine. Lack of major effects of the compounds evaluated could be due to intracellular synthesis of thiamine covering most requirements.
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