Význam TDM, fenotypizace a genotypizace pro správné dávkování léciv
[Significance of TDM, phenotyping and genotyping for the correct drug dosage]
Casopis lekaru ceskych.
2010 ;
149 (10) :
482-7.
Language Czech Country Czech Republic Media print
Document type English Abstract, Journal Article, Review
Persistent link
https://www.medvik.cz/link/pmid21121139
PubMed
21121139
- MeSH
- Pharmacokinetics MeSH
- Phenotype * MeSH
- Genotype * MeSH
- Precision Medicine * MeSH
- Humans MeSH
- Drug Monitoring * MeSH
- Drug Dosage Calculations * MeSH
- Check Tag
- Humans MeSH
- Publication type
- English Abstract MeSH
- Journal Article MeSH
- Review MeSH
Therapeutic drug monitoring is a specific method of clinical pharmacology for monitoring of the therapy using measurement of drug serum concentrations followed by interpretation and good cooperation with clinician. It significantly helps to personalize and rationalize the treatment, to set individualized dosing, to minimize side effects, to decrease mortality and morbidity and to decrease the costs. Phenotyping and genotyping can increase therapeutic drug monitoring on higher level.
Medicine.
2016 Mar ;
95 (9) :
e2881.
