Traumatic stress, dissociation, and limbic irritability in patients with unipolar depression being treated with SSRIs
Language English Country United States Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Antidepressive Agents therapeutic use MeSH
- Depressive Disorder drug therapy psychology MeSH
- Dissociative Disorders psychology MeSH
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Surveys and Questionnaires MeSH
- Psychiatric Status Rating Scales MeSH
- Stress, Psychological psychology MeSH
- Psychometrics MeSH
- Selective Serotonin Reuptake Inhibitors therapeutic use MeSH
- Life Change Events MeSH
- Self Report MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antidepressive Agents MeSH
- Serotonin Uptake Inhibitors MeSH
Recent evidence suggests that stressful experiences may be related to deficits in inhibitory functions and temporo-limbic epileptic-like activity. The latter may produce psychosensory seizure-like symptoms that may also appear in nonepileptic conditions. This study assesses whether the increased presence of the seizure-like symptoms in 113 unipolar depressive patients treated with SSRIs is associated with significantly more severe symptoms of depression, traumatic stress, and dissociation in comparison with 86 healthy controls. Results indicate that seizure-like symptoms in depressive patients have significant association with depression, symptoms of dissociation, and traumatic stress. This association suggests that processess generating seizure-like symptoms may be related to symptoms of depression, traumatic stress, and dissociation.
References provided by Crossref.org
Stress, epileptiform symptoms in schizophrenia and neural information transmission
