Screening of Staphylococcus aureus nasal strains isolated from medical students for toxin genes
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články
- MeSH
- bakteriální léková rezistence MeSH
- bakteriální toxiny genetika MeSH
- enterotoxiny analýza MeSH
- exfoliatiny analýza MeSH
- exotoxiny MeSH
- leukocidiny MeSH
- lidé MeSH
- mikrobiální testy citlivosti MeSH
- nos mikrobiologie MeSH
- přenašečství * MeSH
- Staphylococcus aureus účinky léků genetika izolace a purifikace MeSH
- studenti lékařství MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- Názvy látek
- bakteriální toxiny MeSH
- enterotoxiny MeSH
- exfoliatiny MeSH
- exotoxiny MeSH
- leukocidiny MeSH
- Panton-Valentine leukocidin MeSH Prohlížeč
Three hundred twenty-one students (156 students with no clinical exposure and 165 students with clinical exposure) were screened for nasal colonization by Staphylococcus aureus; 20.9% of students were S. aureus nasal carriers, and 40.3% of S. aureus isolates harbored toxin genes. The most prevalent genes were tst (15.0 %) and sec (13.4 %). Isolates with multiple genes were only found among clinical students (p = 0.045). Six of 11 PFGE clones were positive for toxin genes. Methicillin-resistant (MRSA) isolates were only detected in the clinical students (4.5 %). The exposure of students to the hospital environment neither radically increased S. aureus nasal carriage, nor the frequency of clinically important toxin gene presence, but it could have influenced the positive selection of toxigenic MRSA strains.
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