Theory predicts that naturally occurring hybrid zones between genetically distinct taxa can move over space and time as a result of selection and/or demographic processes, with certain types of hybrid zones being more or less likely to move. Determining whether a hybrid zone is stationary or moving has important implications for understanding evolutionary processes affecting interactions in hybrid populations. However, direct observations of hybrid zone movement are difficult to make unless the zone is moving rapidly. Here, evidence for movement in the house mouse Mus musculus domesticus × Mus musculus musculus hybrid zone is provided using measures of LD and haplotype structure among neighbouring SNP markers from across the genome. Local populations of mice across two transects in Germany and the Czech Republic were sampled, and a total of 1301 mice were genotyped at 1401 markers from the nuclear genome. Empirical measures of LD provide evidence for extinction and (re)colonization in single populations and, together with simulations, suggest hybrid zone movement because of either geography-dependent asymmetrical dispersal or selection favouring one subspecies over the other.

Department of Ecology and Evolutionary Biology and Museum of Zoology University of Michigan Ann Arbor MI 48109 USA

References provided by Crossref.org

Genic and chromosomal components of Prdm9-driven hybrid male sterility in mice (Mus musculus)

Testing parasite 'intimacy': the whipworm Trichuris muris in the European house mouse hybrid zone

Functional organization of the genome may shape the species boundary in the house mouse

Murine cytomegalovirus is not restricted to the house mouse Mus musculus domesticus: prevalence and genetic diversity in the European house mouse hybrid zone

Coevolution of Cryptosporidium tyzzeri and the house mouse (Mus musculus)

Sperm-related phenotypes implicated in both maintenance and breakdown of a natural species barrier in the house mouse

Genome-wide architecture of reproductive isolation in a naturally occurring hybrid zone between Mus musculus musculus and M. m. domesticus