The effect of a cardiopulmonary bypass system with biocompatible coating on fibrinogen levels determined by the TEG--functional fibrinogen method: preliminary results
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
21742756
DOI
10.1177/0267659111415891
PII: 0267659111415891
Knihovny.cz E-resources
- MeSH
- Coated Materials, Biocompatible metabolism MeSH
- Adult MeSH
- Fibrinogen metabolism MeSH
- Heparin metabolism MeSH
- Cardiopulmonary Bypass instrumentation MeSH
- Middle Aged MeSH
- Humans MeSH
- Aged MeSH
- Thrombelastography MeSH
- Check Tag
- Adult MeSH
- Middle Aged MeSH
- Humans MeSH
- Male MeSH
- Aged MeSH
- Female MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Coated Materials, Biocompatible MeSH
- Fibrinogen MeSH
- Heparin MeSH
When cardiopulmonary bypass (CPB) is used, the blood comes into contact with foreign surfaces. To diminish this impact, various types of biocompatibly coated surfaces have been developed. The study assessed the effects of heparin-coated CPB systems on the level and function of fibrinogen as measured by thromboelastography (TEG), as compared with non-coated systems. No statistically significant differences between both groups were revealed by comparing paired data. In our study, heparin-coated CPB circuits had no significant effect on either fibrinogen level or its function.
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