Flow cytometry in monoclonal gammopathies
Language English Country Czech Republic Media print
Document type Journal Article, Research Support, Non-U.S. Gov't, Review
PubMed
21923060
Knihovny.cz E-resources
- MeSH
- Antigens, CD analysis MeSH
- Immunophenotyping MeSH
- Humans MeSH
- Paraproteinemias immunology pathology MeSH
- Plasma Cells classification immunology MeSH
- Flow Cytometry * methods standards MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Review MeSH
- Names of Substances
- Antigens, CD MeSH
The technological development of flow cytometry (FC) together with new findings reveal the need for immunophenotyping in research of monoclonal gammopathy (MG) because of its diagnostic, prognostic and predictive significance. The aim of the European Myeloma Network (EMN) is to standardize this analytical method and implement it into routine clinical examination. Since the overall significance and application of FC are still analysed, standardisation could help obtain more clinical relevant information in terms of MG pathophysiology.