Management of antiplatelet therapy inpatients at risk for coronary StentThrombosis undergoing non-cardiac surgery
Jazyk angličtina Země Nový Zéland Médium print
Typ dokumentu časopisecké články, práce podpořená grantem, přehledy
PubMed
21942972
DOI
10.2165/11594260-000000000-00000
PII: 1
Knihovny.cz E-zdroje
- MeSH
- Aspirin aplikace a dávkování MeSH
- časové faktory MeSH
- cévní protézy škodlivé účinky MeSH
- chirurgie operační * MeSH
- hospitalizovaní pacienti MeSH
- inhibitory agregace trombocytů aplikace a dávkování MeSH
- kombinovaná farmakoterapie MeSH
- koronární trombóza etiologie terapie MeSH
- lidé MeSH
- pyridiny aplikace a dávkování MeSH
- rizikové faktory MeSH
- stenty škodlivé účinky MeSH
- Check Tag
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- Aspirin MeSH
- inhibitory agregace trombocytů MeSH
- pyridiny MeSH
- thienopyridine MeSH Prohlížeč
Percutaneous coronary interventions (PCIs) have become the most commonly performed coronary revascularization procedures. At the same time, there is an increased likelihood that patients with intracoronary stents will need to undergo surgery. Two serious consequences emerge from this situation: (i) stent thrombosis in relation to discontinuation of antiplatelet therapy, and (ii) major bleeding in relation to continuation of antiplatelet therapy. The best solution to overcome the risks resulting from surgery performed in patients after stent implantation is to postpone the operation until after re-endothelialization of the vessel surface is completed. Expert recommendations advise that patients can be sent for non-cardiac surgery 3 months after bare-metal stent PCI and 12 months after drug-eluting stent PCI, with continuation of aspirin therapy. Difficult decisions regarding antiplatelet management arise when a patient that is still receiving dual antiplatelet therapy with aspirin and a thienopyridine has to undergo surgery that cannot be postponed. Discussions between the treating cardiologist, the surgeon and the anaesthesiologist about this situation are recommended in order to achieve a reasonable expert consensus.
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