Scedosporium and Pseudallescheria low molecular weight metabolites revealed by database search
Language English Country Germany Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Peptides, Cyclic chemistry MeSH
- Databases, Factual * MeSH
- Lipids chemistry MeSH
- Metabolomics MeSH
- Molecular Weight MeSH
- Pseudallescheria chemistry metabolism MeSH
- Scedosporium chemistry metabolism MeSH
- Software * MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Peptides, Cyclic MeSH
- Lipids MeSH
The potential of mMass software search tool with new compound libraries was demonstrated on metabolomics of Scedosporium prolificans, S. apiospermum and Pseudallescheria boydii sensu stricto. Cyclic peptides pseudacyclins, small molecular weight tyroscherin analogues and various lipids were annotated by public software tool (http://www.mmass.org) utilising accurate matrix-assisted laser desorption/ionisation mass spectral data of intact fungal spores. Electrospray ionisation combined with tandem mass spectrometry was used for monohexosylceramide characterisation in fungal extracts.
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