Laparoscopic greater curvature plication (LGCP) for treatment of morbid obesity in a series of 244 patients
Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
- MeSH
- analýza rozptylu MeSH
- diabetes mellitus 2. typu krev komplikace patofyziologie MeSH
- gastroplastika škodlivé účinky metody MeSH
- hmotnostní úbytek MeSH
- index tělesné hmotnosti MeSH
- laparoskopie * MeSH
- lidé středního věku MeSH
- lidé MeSH
- logistické modely MeSH
- morbidní obezita krev komplikace patofyziologie chirurgie MeSH
- následné studie MeSH
- prospektivní studie MeSH
- výsledek terapie MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
BACKGROUND: Laparoscopic greater curvature plication (LGCP) is a new metabolic/bariatric surgical procedure that requires no resection, bypass, or implantable device. We report LGCP outcomes in 244 morbidly obese patients. METHODS: Between 2010 and 2011, patients underwent LGCP. Body mass index (BMI, kilogram per square meter) evolution, excess BMI loss (%EBMIL), excess weight loss (%EWL), complications, and type 2 diabetes mellitus (T2DM) changes were recorded. Repeated-measures analysis of variance (ANOVA) was used to assess weight change at 6, 12, and 18 months. Subgroup analyses were conducted to provide benchmark outcomes at 6 months. Logistic regression was used to identify characteristics predictive of suboptimal weight loss. RESULTS: Mean baseline BMI (±SD) was 41.4 ± 5.5 (80.7 % women, mean age 46.1 ± 11.0 years, 68 [27.9 %] patients had T2DM). Mean operative time was 70.6 min; mean hospitalization, 36 h (24-72). Sixty-eight patients (27.9 %) experienced postoperative nausea and/or vomiting that was controlled within 36 h. There was no mortality. Major complication rate was 1.2 % (n = 3). Repeated-measures ANOVA indicated significant weight loss across time points (p < 0.001). At 6 months (n = 105), BMI, %EBMIL, and %EWL were 36.1 ± 4.7, 34.8 ± 17.3, and 31.8 ± 15.9. Preoperative BMI was the only predictor of weight loss. Patients with BMI <40 lost more weight than those ≥40, although by 9 months, differences were no longer significant. In patients with preoperative BMI <40, 18-month %EWL approached 50 % and %EBMIL exceeded 50 %. At 6 months, 96.9 % of patients' T2DM was significantly improved/resolved. CONCLUSIONS: Over the short term, LGCP results in effective weight loss and significant T2DM reduction with a very low rate of complications.
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Surg Obes Relat Dis. 2008 Sep-Oct;4(5 Suppl):S109-84 PubMed
Obes Surg. 2005 Aug;15(7):1034-9 PubMed
Surg Obes Relat Dis. 2009 Jul-Aug;5(4):469-75 PubMed
Surg Obes Relat Dis. 2007 Jan-Feb;3(1):73-7; discussion 77 PubMed
Surg Obes Relat Dis. 2011 Jan-Feb;7(1):8-14 PubMed
J Laparoendosc Adv Surg Tech A. 2007 Dec;17(6):793-8 PubMed
Obes Surg. 2007 May;17(5):565-8 PubMed
N Engl J Med. 2007 Aug 23;357(8):741-52 PubMed
Cir Esp. 2011 Jun-Jul;89(6):356-61 PubMed
Ann Intern Med. 1991 Dec 15;115(12):956-61 PubMed
Obes Surg. 2007 Oct;17(10):1340-5 PubMed
J Clin Invest. 2007 Jan;117(1):13-23 PubMed
Br J Surg. 1969 Dec;56(12):930-3 PubMed
Obes Surg. 2011 Nov;21(11):1657-63 PubMed
Int J Obes (Lond). 2007 Aug;31(8):1248-61 PubMed
Surg Obes Relat Dis. 2011 Jan-Feb;7(1):15-22 PubMed
Surg Endosc. 2005 Jan;19(1):15-20 PubMed
Ann Surg. 2004 Sep;240(3):416-23; discussion 423-4 PubMed
Obes Surg. 2006 Feb;16(2):172-7 PubMed
Obesity (Silver Spring). 2007 May;15(5):1187-98 PubMed
Obes Surg. 2010 Jul;20(7):913-8 PubMed
Surg Obes Relat Dis. 2011 May-Jun;7(3):262 PubMed
JAMA. 2004 Oct 13;292(14):1724-37 PubMed
Surg Obes Relat Dis. 2005 Jan-Feb;1(1):67-8 PubMed
Five-Year Outcomes: Laparoscopic Greater Curvature Plication for Treatment of Morbid Obesity
Interdisciplinary European guidelines on metabolic and bariatric surgery
Interdisciplinary European Guidelines on metabolic and bariatric surgery
