Glycogen as a biodegradable construction nanomaterial for in vivo use
Language English Country Germany Media print-electronic
Document type Comparative Study, Journal Article, Research Support, Non-U.S. Gov't
- MeSH
- Biocompatible Materials chemistry MeSH
- Fluorescence MeSH
- Gadolinium MeSH
- Glycogen chemistry MeSH
- Heterocyclic Compounds MeSH
- Drug Delivery Systems methods MeSH
- Molecular Imaging methods MeSH
- Nanostructures chemistry MeSH
- Organometallic Compounds MeSH
- Microscopy, Electron, Transmission MeSH
- Animals MeSH
- Check Tag
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Comparative Study MeSH
- Names of Substances
- Biocompatible Materials MeSH
- gadolinium 1,4,7,10-tetraazacyclododecane-N,N',N'',N'''-tetraacetate MeSH Browser
- Gadolinium MeSH
- Glycogen MeSH
- Heterocyclic Compounds MeSH
- Organometallic Compounds MeSH
It is demonstrated that glycogen as a biodegradable and inexpensive material coming from renewable resources can be used as a carrier for the construction of in vivo imaging nanoagents. The model system considered is composed of glycogen modified with gadolinium and fluorescent labels. Systematic studies of properties of these nanocarriers by a variety of physical methods and results of in vivo tests of biodegradability are reported. This represents, to the authors' best knowledge, the first such use of glycogen.
References provided by Crossref.org
Glycogen as an advantageous polymer carrier in cancer theranostics: Straightforward in vivo evidence
Biological characterization of a novel hybrid copolymer carrier system based on glycogen
