Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L.)
Jazyk angličtina Země Švédsko Médium print
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
23353856
PII: NEL330912A19
Knihovny.cz E-zdroje
- MeSH
- antioxidancia metabolismus MeSH
- biologické markery metabolismus MeSH
- chemické látky znečišťující vodu toxicita MeSH
- embryo nesavčí účinky léků metabolismus MeSH
- glutathionreduktasa metabolismus MeSH
- herbicidy toxicita MeSH
- kapři embryologie metabolismus MeSH
- katalasa metabolismus MeSH
- látky reagující s kyselinou thiobarbiturovou metabolismus MeSH
- oxidační stres účinky léků fyziologie MeSH
- prometryn toxicita MeSH
- řeky chemie MeSH
- superoxiddismutasa metabolismus MeSH
- testy chronické toxicity MeSH
- zvířata MeSH
- Check Tag
- mužské pohlaví MeSH
- ženské pohlaví MeSH
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Geografické názvy
- Česká republika MeSH
- Názvy látek
- antioxidancia MeSH
- biologické markery MeSH
- chemické látky znečišťující vodu MeSH
- glutathionreduktasa MeSH
- herbicidy MeSH
- katalasa MeSH
- látky reagující s kyselinou thiobarbiturovou MeSH
- prometryn MeSH
- superoxiddismutasa MeSH
OBJECTIVES: The aim of the study was to investigate effects of the triazine herbicide prometryne on early life stages of common carp Cyprinus carpio as indicated by oxidative stress and antioxidant indices. DESIGN: Toxicity tests were performed according to OECD 210 methodologies. Common carp larvae and embryos exposed for 35 days to prometryne at three concentrations, 0.51 (reported concentration in Czech rivers), 80 (1% 96 h LC50), and 1200 (15% 96 h LC50) μg/l, were compared to carp in a non-treated control group. Activity of superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GR), as well as levels of thiobarbituric acid reactive substances (TBARS) were assessed. RESULTS: Chronic exposure of early life stages of carp to prometryne showed no effect on growth and mortality rates. Levels of oxidative damage in fish test groups showed no significant differences from the controls. Glutathione reductase activity at exposure 0.51 μg/l was significantly increase (p<0.01) compared with controls and other exposures. CONCLUSION: The chronic exposure to prometryne showed no influence on oxidative stress. Differences from control fish was observed in GR activity in exposure prometryne 0.51 μg/l.
Effects of praziquantel on common carp embryos and larvae