Effect of chronic exposure to prometryne on oxidative stress and antioxidant response in early life stages of common carp (Cyprinus carpio L.)
Language English Country Sweden Media print
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
23353856
PII: NEL330912A19
Knihovny.cz E-resources
- MeSH
- Antioxidants metabolism MeSH
- Biomarkers metabolism MeSH
- Water Pollutants, Chemical toxicity MeSH
- Embryo, Nonmammalian drug effects metabolism MeSH
- Glutathione Reductase metabolism MeSH
- Herbicides toxicity MeSH
- Carps embryology metabolism MeSH
- Catalase metabolism MeSH
- Thiobarbituric Acid Reactive Substances metabolism MeSH
- Oxidative Stress drug effects physiology MeSH
- Prometryne toxicity MeSH
- Rivers chemistry MeSH
- Superoxide Dismutase metabolism MeSH
- Toxicity Tests, Chronic MeSH
- Animals MeSH
- Check Tag
- Male MeSH
- Female MeSH
- Animals MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Geographicals
- Czech Republic MeSH
- Names of Substances
- Antioxidants MeSH
- Biomarkers MeSH
- Water Pollutants, Chemical MeSH
- Glutathione Reductase MeSH
- Herbicides MeSH
- Catalase MeSH
- Thiobarbituric Acid Reactive Substances MeSH
- Prometryne MeSH
- Superoxide Dismutase MeSH
OBJECTIVES: The aim of the study was to investigate effects of the triazine herbicide prometryne on early life stages of common carp Cyprinus carpio as indicated by oxidative stress and antioxidant indices. DESIGN: Toxicity tests were performed according to OECD 210 methodologies. Common carp larvae and embryos exposed for 35 days to prometryne at three concentrations, 0.51 (reported concentration in Czech rivers), 80 (1% 96 h LC50), and 1200 (15% 96 h LC50) μg/l, were compared to carp in a non-treated control group. Activity of superoxide dismutase (SOD), catalase (CAT), and glutathione reductase (GR), as well as levels of thiobarbituric acid reactive substances (TBARS) were assessed. RESULTS: Chronic exposure of early life stages of carp to prometryne showed no effect on growth and mortality rates. Levels of oxidative damage in fish test groups showed no significant differences from the controls. Glutathione reductase activity at exposure 0.51 μg/l was significantly increase (p<0.01) compared with controls and other exposures. CONCLUSION: The chronic exposure to prometryne showed no influence on oxidative stress. Differences from control fish was observed in GR activity in exposure prometryne 0.51 μg/l.
Effects of praziquantel on common carp embryos and larvae