Gompertz - A program for evaluation and comparison of survival curves
Status PubMed-not-MEDLINE Jazyk angličtina Země Spojené státy americké Médium print
Typ dokumentu časopisecké články
PubMed
23604852
PubMed Central
PMC3455601
DOI
10.1007/s11357-000-0014-9
PII: 14
Knihovny.cz E-zdroje
- Publikační typ
- časopisecké články MeSH
Principles, properties and use of a program for evaluation of survival curves are described. Parameters of Gompertzian mortality curves are computed from survival data of two populations by help of nonlinear regression. The differences in parameters of both curves are evaluated statistically. This method evaluates effectively even survival data of very small populations. The results are presented in numeric, verbal and graphic forms. Finally, reading of the results is offered to distinguish changes corresponding to altered aging rate from changes caused by influences not affecting the basic mechanism of aging. Program GOMPERTZ in the form of Microsoft Excel workbook equipped with Visual Basic procedures is offered free through e-mail (klemera@faf.cuni.cz).
Zobrazit více v PubMed
Gompertz B. On the nature of the function expressive the law of human mortality. Philos. Trans. R. Soc. London. 1825;115:513–585. PubMed
Riggs J.E. Longitudinal Gompertzian analysis of adult mortality in the US 1900–1986. Mech. Ageing Dev. 1990;54:235–247. doi: 10.1016/0047-6374(90)90053-I. PubMed DOI
Strehler B.L. Time, cells and aging. New York: Academic Press; 1977.
Doubal S. Theory of reliability, biological systems and ageing. Mech. Ageing Dev. 1982;18:339–353. doi: 10.1016/0047-6374(82)90037-9. PubMed DOI
Dolejs J. The extension of Gompertz law?s validity. Mech. Ageing Dev. 1997;99:233–244. doi: 10.1016/S0047-6374(97)00104-8. PubMed DOI
Carey, JR: Slowing of mortality rates at older ages in large medfly cohorts. Science 255–258, 1992. PubMed
Smith D.W.E. The tails of survival curves. BioEssays. 1994;16:907–911. doi: 10.1002/bies.950161209. PubMed DOI
Klemera P., Doubal S. Human mortality at very advanced age might be constant. Mech. Ageing Dev. 1997;98:167–176. doi: 10.1016/S0047-6374(97)00081-X. PubMed DOI
Bazaraa S., Shetty C.M. Theory and algorithms. New York: John Wiley and Sons; 1979. Nonlinear programming.
Nash J.C., Walker-Smith M. An integrated system in BASIC. New York: Marcel Dekker, Inc.; 1987. Nonlinear parameter estimation; p. 259.
Dowdy S., Wearden S. Statistics for research. New York: John Wiley and Sons; 1983. p. 188.
Hart B.I. Significance levels for the ratio of the mean square successive difference to the variance. Annals Math. Statistics. 1942;13:445–447.
Doubal S., Klemera P. Influence of aging rate on mortality curves. Mech. Ageing Dev. 1990;54:75–58. doi: 10.1016/0047-6374(90)90017-A. PubMed DOI
Doubal S., Klemera P. Practical methodology of evaluation of mortality curves and detection of aging-related interventions. Age. 1997;20:229–233. PubMed PMC
