Correlation between the activity of digestive enzymes and nonself recognition in the gut of Eisenia andrei earthworms
Jazyk angličtina Země Spojené státy americké Médium print-electronic
Typ dokumentu časopisecké články, práce podpořená grantem
PubMed
23999244
DOI
10.1016/j.jip.2013.08.003
PII: S0022-2011(13)00116-X
Knihovny.cz E-zdroje
- Klíčová slova
- Digestive enzyme, Earthworm, Eisenia andrei, Gut, Innate immunity, Microbiota,
- MeSH
- Bacillus subtilis imunologie MeSH
- celulasy metabolismus MeSH
- Escherichia coli imunologie MeSH
- hexosaminidasy metabolismus MeSH
- messenger RNA metabolismus MeSH
- muramidasa metabolismus fyziologie MeSH
- Oligochaeta enzymologie imunologie mikrobiologie MeSH
- přirozená imunita MeSH
- proteasy metabolismus MeSH
- Saccharomyces cerevisiae imunologie MeSH
- upregulace MeSH
- zvířata MeSH
- Check Tag
- zvířata MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- Názvy látek
- celulasy MeSH
- hexosaminidasy MeSH
- messenger RNA MeSH
- muramidasa MeSH
- proteasy MeSH
Earthworms Eisenia andrei, similarly to other invertebrates, rely on innate defense mechanisms based on the capability to recognize and respond to nonself. Here, we show a correlation between the expression of CCF, a crucial pattern-recognition receptor, and lysozyme, with enzyme activities in the gut of E. andrei earthworms following a microbial challenge. These data suggest that enzyme activities important for the release and recognition of molecular patterns by pattern-recognition molecules, as well as enzymes involved in effector pathways, are modulated during the microbial challenge. In particular, protease, laminarinase, and glucosaminidase activities were increased in parallel to up-regulated CCF and lysozyme expression.
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