Low contrast volume run-off CT angiography with optimized scan time based on double-level test bolus technique--feasibility study
Jazyk angličtina Země Irsko Médium print-electronic
Typ dokumentu časopisecké články, randomizované kontrolované studie, práce podpořená grantem
PubMed
24380637
DOI
10.1016/j.ejrad.2013.12.004
PII: S0720-048X(13)00645-1
Knihovny.cz E-zdroje
- Klíčová slova
- CT angiography, Contrast medium, Peripheral vascular disease, Run-off, Test bolus,
- MeSH
- algoritmy * MeSH
- angiografie metody MeSH
- injekce intraarteriální MeSH
- interpretace obrazu počítačem metody MeSH
- kontrastní látky aplikace a dávkování MeSH
- lidé středního věku MeSH
- lidé MeSH
- onemocnění periferních arterií diagnostické zobrazování MeSH
- počítačová rentgenová tomografie metody MeSH
- reprodukovatelnost výsledků MeSH
- senzitivita a specificita MeSH
- studie proveditelnosti MeSH
- vylepšení obrazu metody MeSH
- vztah mezi dávkou a účinkem léčiva MeSH
- Check Tag
- lidé středního věku MeSH
- lidé MeSH
- Publikační typ
- časopisecké články MeSH
- práce podpořená grantem MeSH
- randomizované kontrolované studie MeSH
- Názvy látek
- kontrastní látky MeSH
PURPOSE: To verify the technical feasibility of low contrast volume (40 mL) run-off CT angiography (run-off CTA) with the individual scan time optimization based on double-level test bolus technique. MATERIALS AND METHODS: A prospective study of 92 consecutive patients who underwent run-off CTA performed with 40 mL of contrast medium (injection rate of 6 mL/s) and optimized scan times on a second generation of dual-source CT. Individual optimized scan times were calculated from aortopopliteal transit times obtained on the basis of double-level test bolus technique--the single injection of 10 mL test bolus and dynamic acquisitions in two levels (abdominal aorta and popliteal arteries). Intraluminal attenuation (HU) was measured in 6 levels (aorta, iliac, femoral and popliteal arteries, middle and distal lower-legs) and subjective quality (3-point score) was assessed. Relations of image quality, test bolus parameters and arterial circulation involvement were analyzed. RESULTS: High mean attenuation (HU) values (468; 437; 442; 440; 342; 274) and quality score in all monitored levels was achieved. In 91 patients (0.99) the sufficient diagnostic quality (score 1-2) in aorta, iliac and femoral arteries was determined. A total of 6 patients (0.07) were not evaluable in distal lower-legs. Only the weak indirect correlation of image quality and test-bolus parameters was proved in iliac, femoral and popliteal levels (r values: -0.263, -0.298 and -0.254). The statistically significant difference of the test-bolus parameters and image quality was proved in patients with occlusive and aneurysmal disease. CONCLUSION: We proved the technical feasibility and sufficient quality of run-off CTA with low volume of contrast medium and optimized scan time according to aortopopliteal transit time calculated from double-level test bolus.
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