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Breast cancer in the elderly-Should it be treated differently?

. 2012 Jul 15 ; 18 (1) : 26-33. [epub] 20120715

Status PubMed-not-MEDLINE Language English Country Poland Media electronic

Document type Journal Article, Review

Links

PubMed 24381744
PubMed Central PMC3863252
DOI 10.1016/j.rpor.2012.05.005
PII: S1507-1367(12)00083-1
Knihovny.cz E-resources

Breast cancer risk increases with age and about a third of female breast cancers are diagnosed in patients aged older than 70. Breast cancer in the elderly has, however, poorer outcome with lower survival rate compared to younger subjects. This may be partly explained by the delay in diagnosis and the 'under-treatment' of elderly breast cancer patients. In this review I try to provide recommendations for screening, surgery, radiotherapy, (neo)adjuvant hormone treatment and chemotherapy, and also the treatment of metastatic disease. Since large randomised trials usually exclude elderly patients with breast cancer, there is still an insufficient evidence for the treatment of such patients.

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