Effect of meditation on cognitive functions in context of aging and neurodegenerative diseases

. 2014 ; 8 () : 17. [epub] 20140127

Status PubMed-not-MEDLINE Jazyk angličtina Země Švýcarsko Médium electronic-ecollection

Typ dokumentu časopisecké články, přehledy

Perzistentní odkaz   https://www.medvik.cz/link/pmid24478663

Effect of different meditation practices on various aspects of mental and physical health is receiving growing attention. The present paper reviews evidence on the effects of several mediation practices on cognitive functions in the context of aging and neurodegenerative diseases. The effect of meditation in this area is still poorly explored. Seven studies were detected through the databases search, which explores the effect of meditation on attention, memory, executive functions, and other miscellaneous measures of cognition in a sample of older people and people suffering from neurodegenerative diseases. Overall, reviewed studies suggested a positive effect of meditation techniques, particularly in the area of attention, as well as memory, verbal fluency, and cognitive flexibility. These findings are discussed in the context of MRI studies suggesting structural correlates of the effects. Meditation can be a potentially suitable non-pharmacological intervention aimed at the prevention of cognitive decline in the elderly. However, the conclusions of these studies are limited by their methodological flaws and differences of various types of meditation techniques. Further research in this direction could help to verify the validity of the findings and clarify the problematic aspects.

Zobrazit více v PubMed

Alexander C. N., Langer E. J., Newman R. I., Chandler H. M., Davies J. L. (1989). Transcendental meditation, mindfulness, and longevity: an experimental study with the elderly. J. Pers. Soc. Psychol. 57, 950–96410.1037/0022-3514.57.6.950 PubMed DOI

Anderson J. W., Liu C., Kryscio R. J. (2008). Blood pressure response to transcendental meditation: a meta-analysis. Am. J. Hypertens. 21, 310–31610.1038/ajh.2007.65 PubMed DOI

Balaji P. A., Varne S. R., Ali S. S. (2012). Physiological effects of yogic practices and transcendental meditation in health and disease. N. Am. J. Med. Sci. 4, 442–44810.4103/1947-2714.101980 PubMed DOI PMC

Barnes V. A., Treiber F. A., Davis H. (2001). Impact of transcendental meditation on cardiovascular function at rest and during acute stress in adolescents with high normal blood pressure. J. Psychosom. Res. 51, 597–60510.1016/S0022-3999(01)00261-6 PubMed DOI PMC

Beaudreau S. A., O’Hara R. (2008). Late-life anxiety and cognitive impairment: a review. Am. J. Geriatr. Psychiatry 16, 790–80310.1097/JGP.0b013e31817945c3 PubMed DOI

Benson H., Greenwood M. M., Klemchuk H. (1975). The relaxation response: psychophysiologic aspects and clinical applications. Int. J. Psychiatry Med. 6, 87–9810.2190/376W-E4MT-QM6Q-H0UM PubMed DOI

Brookmeyer R., Johnson E., Ziegler-Graham K., Arrighi H. M. (2007). Forecasting the global burden of Alzheimer’s disease. Alzheimers Dement. 3, 186–19110.1016/j.jalz.2007.04.381 PubMed DOI

Chien L. Y., Chu H., Guo J. L., Liao Y. M., Chang L. I., Chen C. H., et al. (2011). Caregiver support groups in patients with dementia: a meta-analysis. Int. J. Geriatr. Psychiatry 26, 1089–109810.1002/gps.2660 PubMed DOI

Chiesa A., Calati R., Serretti A. (2011). Does mindfulness training improve cognitive abilities? A systematic review of neuropsychological findings. Clin. Psychol. Rev. 31, 449–46410.1016/j.cpr.2010.11.003 PubMed DOI

Christensen K., Thinggaard M., Oksuzyan A., Steenstrup T., Andersen-Ranberg K., Jeune B., et al. (2013). Physical and cognitive functioning of people older than 90 years: a comparison of two Danish cohorts born 10 years apart. Lancet 382, 1507–151310.1016/S0140-6736(13)60777-1 PubMed DOI PMC

Dopson L. (2005). Spirituality and Alzheimer’s. Nurs. Older People 17, 39.10.7748/nop2005.05.17.3.39.c2374 PubMed DOI

Epel E., Daubenmier J., Moskowitz J. T., Folkman S., Blackburn E. (2009). Can meditation slow rate of cellular aging? Cognitive stress, mindfulness, and telomeres. Ann. N. Y. Acad. Sci. 1172, 34–5310.1111/j.1749-6632.2009.04414.x PubMed DOI PMC

Forem J. (2012). Transcendental Meditation. London: Hay House Inc

Forette F., Seux M. L., Staessen J. A., Thijs L., Birkenhager W. H., Babarskiene M. R., et al. (1998). Prevention of dementia in randomised double-blind placebo-controlled systolic hypertension in Europe (Syst-Eur) trial. Lancet 352, 1347–135110.1016/S0140-6736(98)03086-4 PubMed DOI

Gauthier S., Cummings J., Ballard C., Brodaty H., Grossberg G., Robert P., et al. (2010). Management of behavioral problems in Alzheimer’s disease. Int. Psychogeriatr. 22, 346–37210.1017/S1041610209991505 PubMed DOI

Georgiou-Karistianis N., Tang J., Vardy Y., Sheppard D., Evans N., Wilson M., et al. (2007). Progressive age-related changes in the attentional blink paradigm. Neuropsychol. Dev. Cogn. B Aging Neuropsychol. Cogn. 14, 213–22610.1080/13825580500320681 PubMed DOI

Germer C. K., Siegel R. D., Fulton P. R. (2005). Mindfulness and Psychotherapy. New York: Guilford Press

Grant J. A., Courtemanche J., Duerden E. G., Duncan G. H., Rainville P. (2010). Cortical thickness and pain sensitivity in Zen meditators. Emotion 10, 43–5310.1037/a0018334 PubMed DOI

Grant J. A., Duerden E. G., Courtemanche J., Cherkasova M., Duncan G. H., Rainville P. (2013). Cortical thickness, mental absorption and meditative practice: possible implications for disorders of attention. Biol. Psychol. 92, 275–28110.1016/j.biopsycho.2012.09.007 PubMed DOI

Grossman P., Niemann L., Schmidt S., Walach H. (2004). Mindfulness-based stress reduction and health benefits. A meta-analysis. J. Psychosom. Res. 57, 35–4310.1016/S0022-3999(03)00573-7 PubMed DOI

Hoge E. A., Chen M. M., Orr E., Metcalf C. A., Fischer L. E., Pollack M. H., et al. (2013). Loving-Kindness Meditation practice associated with longer telomeres in women. Brain Behav. Immun. 32, 159–16310.1016/j.bbi.2013.04.005 PubMed DOI

Holzel B. K., Carmody J., Vangel M., Congleton C., Yerramsetti S. M., Gard T., et al. (2011). Mindfulness practice leads to increases in regional brain gray matter density. Psychiatry Res. 191, 36–4310.1016/j.pscychresns.2010.08.006 PubMed DOI PMC

Holzel B. K., Ott U., Gard T., Hempel H., Weygandt M., Morgen K., et al. (2008). Investigation of mindfulness meditation practitioners with voxel-based morphometry. Soc. Cogn. Affect. Neurosci. 3, 55–6110.1093/scan/nsm038 PubMed DOI PMC

Horrigan B. J. (2007). New studies support the therapeutic value of meditation. Explore (NY) 3, 449–45010.1016/j.explore.2007.07.003 PubMed DOI

Huang W., Qiu C., von Strauss E., Winblad B., Fratiglioni L. (2004). APOE genotype, family history of dementia, and Alzheimer disease risk: a 6-year follow-up study. Arch. Neurol. 61, 1930–193410.1001/archneur.61.12.1930 PubMed DOI

Hulme C., Wright J., Crocker T., Oluboyede Y., House A. (2010). Non-pharmacological approaches for dementia that informal carers might try or access: a systematic review. Int. J. Geriatr. Psychiatry 25, 756–76310.1002/gps.2429 PubMed DOI

Innes K. E., Selfe T. K., Brown C. J., Rose K. M., Thompson-Heisterman A. (2012). The effects of meditation on perceived stress and related indices of psychological status and sympathetic activation in persons with Alzheimer’s disease and their caregivers: a pilot study. Evid. Based Complement. Altern. Med. 2012, 927509.10.1155/2012/927509 PubMed DOI PMC

Jacobs T. L., Epel E. S., Lin J., Blackburn E. H., Wolkowitz O. M., Bridwell D. A., et al. (2011). Intensive meditation training, immune cell telomerase activity, and psychological mediators. Psychoneuroendocrinology 36, 664–68110.1016/j.psyneuen.2010.09.010 PubMed DOI

Jacobs T. L., Shaver P. R., Epel E. S., Zanesco A. P., Aichele S. R., Bridwell D. A., et al. (2013). Self-reported mindfulness and cortisol during a Shamatha meditation retreat. Health Psychol. 32, 1104–110910.1037/a0031362 PubMed DOI

Kabat-Zinn J. (2005). Bringing mindfulness to medicine: an interview with Jon Kabat-Zinn, PhD. Interview by Karolyn Gazella. Adv. Mind Body Med. 21, 22–27 PubMed

Kaufman Y., Anaki D., Binns M., Freedman M. (2007). Cognitive decline in Alzheimer disease: impact of spirituality, religiosity, and QOL. Neurology 68, 1509–151410.1212/01.wnl.0000260697.66617.59 PubMed DOI

Khachaturian A. S., Zandi P. P., Lyketsos C. G., Hayden K. M., Skoog I., Norton M. C., et al. (2006). Antihypertensive medication use and incident Alzheimer disease: the Cache County Study. Arch. Neurol. 63, 686–69210.1001/archneur.63.5.noc60013 PubMed DOI

Khalsa D. S., Amen D., Hanks C., Money N., Newberg A. (2009). Cerebral blood flow changes during chanting meditation. Nucl. Med. Commun. 30, 956–96110.1097/MNM.0b013e32832fa26c PubMed DOI

Khanna S., Greeson J. M. (2013). A narrative review of yoga and mindfulness as complementary therapies for addiction. Complement. Ther. Med. 21, 244–25210.1016/j.ctim.2013.01.008 PubMed DOI PMC

Khatri D., Mathur K. C., Gahlot S., Jain S., Agrawal R. P. (2007). Effects of yoga and meditation on clinical and biochemical parameters of metabolic syndrome. Diabetes Res. Clin. Pract. 78, e9–e1010.1016/j.diabres.2007.05.002 PubMed DOI

Kivipelto M., Helkala E. L., Laakso M. P., Hanninen T., Hallikainen M., Alhainen K., et al. (2001). Midlife vascular risk factors and Alzheimer’s disease in later life: longitudinal, population based study. BMJ 322, 1447–145110.1136/bmj.322.7300.1447 PubMed DOI PMC

Kivipelto M., Ngandu T., Fratiglioni L., Viitanen M., Kareholt I., Winblad B., et al. (2005). Obesity and vascular risk factors at midlife and the risk of dementia and Alzheimer disease. Arch. Neurol. 62, 1556–156010.1001/archneur.62.10.1556 PubMed DOI

Lakhan S. E., Schofield K. L. (2013). Mindfulness-based therapies in the treatment of somatization disorders: a systematic review and meta-analysis. PLoS ONE 8:e71834.10.1371/journal.pone.0071834 PubMed DOI PMC

Langer E. J. (1989). Minding matters: the consequences of mindlessness-mindfulness. Adv. Exp. Soc. Psychol. 22, 137–173

Lavretsky H., Epel E. S., Siddarth P., Nazarian N., Cyr N. S., Khalsa D. S., et al. (2013). A pilot study of yogic meditation for family dementia caregivers with depressive symptoms: effects on mental health, cognition, and telomerase activity. Int. J. Geriatr. Psychiatry 28, 57–6510.1002/gps.3790 PubMed DOI PMC

Lazar S. W., Kerr C. E., Wasserman R. H., Gray J. R., Greve D. N., Treadway M. T., et al. (2005). Meditation experience is associated with increased cortical thickness. Neuroreport 16, 1893–189710.1097/01.wnr.0000186598.66243.19 PubMed DOI PMC

Levin J. S., Taylor R. J., Chatters L. M. (1994). Race and gender differences in religiosity among older adults: findings from four national surveys. J. Gerontol. 49, S137–S14510.1093/geronj/49.3.S137 PubMed DOI

Lindberg D. A. (2005). Integrative review of research related to meditation, spirituality, and the elderly. Geriatr. Nurs. 26, 372–37710.1016/j.gerinurse.2005.09.013 PubMed DOI

Luders E., Clark K., Narr K. L., Toga A. W. (2011). Enhanced brain connectivity in long-term meditation practitioners. Neuroimage 57, 1308–131610.1016/j.neuroimage.2011.05.075 PubMed DOI PMC

Luders E., Thompson P. M., Kurth F., Hong J. Y., Phillips O. R., Wang Y., et al. (2013a). Global and regional alterations of hippocampal anatomy in long-term meditation practitioners. Hum. Brain Mapp. 34, 3369–337510.1002/hbm.22153 PubMed DOI PMC

Luders E., Kurth F., Toga A. W., Narr K. L., Gaser C. (2013b). Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping. Front. Psychol. 4:398.10.3389/fpsyg.2013.00398 PubMed DOI PMC

Luders E., Toga A. W., Lepore N., Gaser C. (2009). The underlying anatomical correlates of long-term meditation: larger hippocampal and frontal volumes of gray matter. Neuroimage 45, 672–67810.1016/j.neuroimage.2008.12.061 PubMed DOI PMC

Lutz A., Slagter H. A., Dunne J. D., Davidson R. J. (2008). Attention regulation and monitoring in meditation. Trends Cogn. Sci. 12, 163–16910.1016/j.tics.2008.01.005 PubMed DOI PMC

Maciokas J. B., Crognale M. A. (2003). Cognitive and attentional changes with age: evidence from attentional blink deficits. Exp. Aging Res. 29, 137–15310.1080/03610730303715 PubMed DOI

Matthews F. E., Arthur A., Barnes L. E., Bond J., Jagger C., Robinson L., et al. (2013). A two-decade comparison of prevalence of dementia in individuals aged 65 years and older from three geographical areas of England: results of the Cognitive Function and Ageing Study I and II. Lancet 382, 1405–141210.1016/S0140-6736(13)61570-6 PubMed DOI PMC

Moss A. S., Wintering N., Roggenkamp H., Khalsa D. S., Waldman M. R., Monti D., et al. (2012). Effects of an 8-week meditation program on mood and anxiety in patients with memory loss. J. Altern. Complement. Med. 18, 48–5310.1089/acm.2011.0051 PubMed DOI

Newberg A., Alavi A., Baime M., Pourdehnad M., Santanna J., d’Aquili E. (2001). The measurement of regional cerebral blood flow during the complex cognitive task of meditation: a preliminary SPECT study. Psychiatry Res. 106, 113–12210.1016/S0925-4927(01)00074-9 PubMed DOI

Newberg A. B., Serruya M., Wintering N., Moss A. S., Reibel D., Monti D. A. (2013). Meditation and neurodegenerative diseases. Ann. N. Y. Acad. Sci. 1307, 112–12310.1111/nyas.12187 PubMed DOI

Newberg A. B., Wintering N., Khalsa D. S., Roggenkamp H., Waldman M. R. (2010a). Meditation effects on cognitive function and cerebral blood flow in subjects with memory loss: a preliminary study. J. Alzheimers Dis. 20, 517–52610.3233/JAD-2010-1391 PubMed DOI

Newberg A. B., Wintering N., Waldman M. R., Amen D., Khalsa D. S., Alavi A. (2010b). Cerebral blood flow differences between long-term meditators and non-meditators. Conscious. Cogn. 19, 899–90510.1016/j.concog.2010.05.003 PubMed DOI

Olazaran J., Reisberg B., Clare L., Cruz I., Pena-Casanova J., Del Ser T., et al. (2010). Nonpharmacological therapies in Alzheimer’s disease: a systematic review of efficacy. Dement. Geriatr. Cogn. Disord. 30, 161–17810.1159/000316119 PubMed DOI

Ospina M. B., Bond K., Karkhaneh M., Tjosvold L., Vandermeer B., Liang Y., et al. (2007). Meditation practices for health: state of the research. Evid. Rep. Technol. Assess. 155, 1–263 PubMed PMC

Pagnoni G., Cekic M. (2007). Age effects on gray matter volume and attentional performance in Zen meditation. Neurobiol. Aging 28, 1623–162710.1016/j.neurobiolaging.2007.06.008 PubMed DOI

Prakash R., Rastogi P., Dubey I., Abhishek P., Chaudhury S., Small B. J. (2012). Long-term concentrative meditation and cognitive performance among older adults. Neuropsychol Dev Cogn B Aging Neuropsychol Cogn. 19, 479–49410.1080/13825585.2011.630932 PubMed DOI

Prince M., Bryce R., Albanese E., Wimo A., Ribeiro W., Ferri C. P. (2013). The global prevalence of dementia: a systematic review and metaanalysis. Alzheimers Dement. 9, 63e–75e10.1016/j.jalz.2012.11.007 PubMed DOI

Qiu C., von Strauss E., Backman L., Winblad B., Fratiglioni L. (2013). Twenty-year changes in dementia occurrence suggest decreasing incidence in central Stockholm, Sweden. Neurology 80, 1888–189410.1212/WNL.0b013e318292a2f9 PubMed DOI

Reitz C. (2013). Dyslipidemia and the risk of Alzheimer’s disease. Curr. Atheroscler. Rep. 15, 307.10.1007/s11883-012-0307-3 PubMed DOI PMC

Rocca W. A., Petersen R. C., Knopman D. S., Hebert L. E., Evans D. A., Hall K. S., et al. (2011). Trends in the incidence and prevalence of Alzheimer’s disease, dementia, and cognitive impairment in the United States. Alzheimers Dement. 7, 80–9310.1016/j.jalz.2010.11.002 PubMed DOI PMC

Roher A. E., Debbins J. P., Malek-Ahmadi M., Chen K., Pipe J. G., Maze S., et al. (2012). Cerebral blood flow in Alzheimer’s disease. Vasc. Health Risk Manag. 8, 599–61110.2147/VHRM.S34874 PubMed DOI PMC

Salthouse T. A. (2011). Neuroanatomical substrates of age-related cognitive decline. Psychol. Bull. 137, 753.10.1037/a0023262 PubMed DOI PMC

Schrijvers E. M., Verhaaren B. F., Koudstaal P. J., Hofman A., Ikram M. A., Breteler M. M. (2012). Is dementia incidence declining? Trends in dementia incidence since 1990 in the Rotterdam Study. Neurology 78, 1456–146310.1212/WNL.0b013e3182553be6 PubMed DOI

Schwartz G. E., Davidson R. J., Goleman D. J. (1978). Patterning of cognitive and somatic processes in the self-regulation of anxiety: effects of meditation versus exercise. Psychosom. Med. 40, 321–328 PubMed

Tang Y. Y., Lu Q., Geng X., Stein E. A., Yang Y., Posner M. I. (2010). Short-term meditation induces white matter changes in the anterior cingulate. Proc. Natl. Acad. Sci. U.S.A. 107, 15649–1565210.1073/pnas.1011043107 PubMed DOI PMC

Turakitwanakan W., Mekseepralard C., Busarakumtragul P. (2013). Effects of mindfulness meditation on serum cortisol of medical students. J. Med. Assoc. Thai. 96(Suppl. 1), S90–S95 PubMed

van Leeuwen S., Muller N. G., Melloni L. (2009). Age effects on attentional blink performance in meditation. Conscious. Cogn. 18, 593–59910.1016/j.concog.2009.05.001 PubMed DOI

Vestergaard-Poulsen P., van Beek M., Skewes J., Bjarkam C. R., Stubberup M., Bertelsen J., et al. (2009). Long-term meditation is associated with increased gray matter density in the brain stem. Neuroreport 20, 170–17410.1097/WNR.0b013e328320012a PubMed DOI

Wachholtz A. B., Pargament K. I. (2005). Is spirituality a critical ingredient of meditation? Comparing the effects of spiritual meditation, secular meditation, and relaxation on spiritual, psychological, cardiac, and pain outcomes. J. Behav. Med. 28, 369–38410.1007/s10865-005-9008-5 PubMed DOI

Waelde L. C., Thompson L., Gallagher-Thompson D. (2004). A pilot study of a yoga and meditation intervention for dementia caregiver stress. J. Clin. Psychol. 60, 677–68710.1002/jclp.10259 PubMed DOI

Wallin K., Bostrom G., Kivipelto M., Gustafson Y. (2013). Risk factors for incident dementia in the very old. Int. Psychogeriatr. 25, 1135–114310.1017/S1041610213000409 PubMed DOI

Walsh R., Shapiro S. L. (2006). The meeting of meditative disciplines and Western psychology: a mutually enriching dialogue. Am. Psychol. 61, 227–23910.1037/0003-066X.61.3.227 PubMed DOI

Walton K. G., Schneider R. H., Nidich S. (2004). Review of controlled research on the transcendental meditation program and cardiovascular disease. Risk factors, morbidity, and mortality. Cardiol. Rev. 12, 262–26610.1097/01.crd.0000113021.96119.78 PubMed DOI PMC

Wang D. J., Rao H., Korczykowski M., Wintering N., Pluta J., Khalsa D. S., et al. (2011). Cerebral blood flow changes associated with different meditation practices and perceived depth of meditation. Psychiatry Res. 191, 60–6710.1016/j.pscychresns.2010.09.011 PubMed DOI

Xiong G. L., Doraiswamy P. M. (2009). Does meditation enhance cognition and brain plasticity? Ann. N. Y. Acad. Sci. 1172, 63–6910.1196/annals.1393.002 PubMed DOI

Najít záznam

Citační ukazatele

Pouze přihlášení uživatelé

Možnosti archivace

Nahrávání dat ...