Biological activities of selected polyphenol-rich fruits related to immunity and gastrointestinal health
Language English Country Great Britain, England Media print-electronic
Document type Journal Article, Research Support, Non-U.S. Gov't
PubMed
24679749
DOI
10.1016/j.foodchem.2014.02.022
PII: S0308-8146(14)00196-4
Knihovny.cz E-resources
- Keywords
- Antimicrobial properties, Antioxidant activity, Mitogenic activity, Oxidative burst, Polyphenols, Small fruits,
- MeSH
- Antioxidants pharmacology MeSH
- Humans MeSH
- Fruit chemistry immunology MeSH
- Polyphenols chemistry MeSH
- Reactive Oxygen Species metabolism MeSH
- Respiratory Burst MeSH
- Plant Extracts chemistry MeSH
- Check Tag
- Humans MeSH
- Publication type
- Journal Article MeSH
- Research Support, Non-U.S. Gov't MeSH
- Names of Substances
- Antioxidants MeSH
- Polyphenols MeSH
- Reactive Oxygen Species MeSH
- Plant Extracts MeSH
Small fruits are a rich source of bioactive substances, including polyphenols, and are therefore suitable raw materials for the production of functional foods. In the current work, we studied the antioxidative properties of six fruits: rosehip, chokeberry, hawthorn, blackcurrant, blueberry and rowanberry via different methods (ORAC, TRAP, HORAC and inhibition of lipid peroxidation). Their effect on the production of reactive oxygen species (ROS) by phagocytes, antimicrobial properties against 11 human pathogens, and mitogenic effect on hamster spleen lymphocytes were also tested. Rosehip extract showed the highest antioxidant activity via ORAC, TRAP and HORAC assays, whereas blueberry extract was the most potent inhibitor of lipid peroxidation. All extracts inhibited ROS production of opsonized zymosan-activated phagocytes, indicating that extracts interfere with the signaling cascade of phagocyte activation upstream to the protein kinase C activation. Chokeberry, blackcurrant and rowanberry extracts revealed strong antimicrobial properties against a broad spectrum of microorganisms and also had the highest mitogenic activity.
Institute of Biophysics of the AS CR Kralovopolska 135 612 65 Brno Czech Republic
University of Food Technologies 26 Maritsa Blvd 4002 Plovdiv Bulgaria
References provided by Crossref.org
The Role of Dietary Phenolic Compounds in Epigenetic Modulation Involved in Inflammatory Processes
