Determination of impurities and counterions of pharmaceuticals by capillary electromigration methods
Jazyk angličtina Země Německo Médium print-electronic
Typ dokumentu hodnotící studie, časopisecké články, práce podpořená grantem, přehledy
PubMed
24838601
DOI
10.1002/jssc.201400266
Knihovny.cz E-zdroje
- Klíčová slova
- Capillary electrophoresis, Chiral impurities, Drug counterions, Drug impurities, Pharmaceutical analysis,
- MeSH
- elektroforéza kapilární metody MeSH
- ionty analýza MeSH
- kontaminace léku prevence a kontrola MeSH
- léčivé přípravky analýza MeSH
- Publikační typ
- časopisecké články MeSH
- hodnotící studie MeSH
- práce podpořená grantem MeSH
- přehledy MeSH
- Názvy látek
- ionty MeSH
- léčivé přípravky MeSH
The review presents a survey of recent applications of high-performance capillary electromigration methods-capillary zone electrophoresis, nonaqueous capillary electrophoresis, capillary isotachophoresis, micellar electrokinetic chromatography, microemulsion electrokinetic chromatography and capillary electrochromatography-for the determination of impurities of pharmaceuticals, including chiral impurities, for the period 2007-2013. In addition, due to the missing evaluation of the determination of counterions of pharmaceuticals by capillary electromigration methods in the last 20 years, the publications dealing with this topic since 1995 are included in this review. General aspects of both these types of applications of capillary electromigration methods in pharmaceutical analysis are discussed, and detailed experimental conditions used for determination of various chemical impurities and counterions of many particular drugs are described.
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